(Q45317003)

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TLR3-mediated TICAM1-dependent programmed cell death

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9013957)

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8 July 2022

Toll Like Receptor 3 (TLR3) Cascade

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-9013957

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8 July 2022

TLR3-induced ripoptosome assembly

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8 July 2022

Caspase-8 processing within TLR3 complex

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8 July 2022

RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis

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8 July 2022

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

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8 July 2022

Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

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8 July 2022

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

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8 July 2022

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

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8 July 2022

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8.

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8 July 2022

Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells

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8 July 2022

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45317003)

TLR3-mediated TICAM1-dependent programmed cell death

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