(Q50291748)

English

RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9013963)

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Statements

biological process

1 reference

8 July 2022

1 reference

8 July 2022

TLR3-mediated TICAM1-dependent programmed cell death

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9013963

1 reference

8 July 2022

Receptor interacting serine/threonine kinase 3

4

object has role

1 reference

8 July 2022

TICAM1:activated TLR3 complexes [endosome membrane]

1

object has role

1 reference

8 July 2022

RIP3:TICAM1:activated TLR3 [endosome membrane]

1

object has role

1 reference

8 July 2022

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

1 reference

8 July 2022

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

1 reference

8 July 2022

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

1 reference

8 July 2022

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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