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Sustained activation of SRC kinase by SHP2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-177923)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
part of
GAB1 signalosome
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-177923
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
exact match
https://identifiers.org/reactome:R-HSA-177923
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
has part(s)
water
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
p-Y-PXN:CSK:MyrG,p-Y530-SRC [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
C-terminal Src kinase
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
PXN:MyrG-SRC [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
hydrogen phosphate ion
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
cites work
A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
Identifiers
Reactome ID
R-HSA-177923
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-177923
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