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SRC-1 phosphorylates SHB
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-4420128)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
part of
VEGFA-VEGFR2 Pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
exact match
https://identifiers.org/reactome:R-HSA-4420128
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
has part(s)
ATP(4-)
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
ADP(3-)
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
SRC proto-oncogene, non-receptor tyrosine kinase
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
cites work
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
Identifiers
Reactome ID
R-HSA-4420128
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4420128
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