(Q50297916)

English

p-6Y-VEGFR2 binds FYN

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5218824)

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Statements

biological process

1 reference

8 July 2022

VEGFA-VEGFR2 Pathway

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5218824

1 reference

8 July 2022

FYN proto-oncogene, Src family tyrosine kinase

1

object has role

1 reference

8 July 2022

VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane]

1

object has role

1 reference

8 July 2022

VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane]

1

object has role

1 reference

8 July 2022

Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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