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p38 MAPK activation by VEGFR
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5218804)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
part of
VEGFA-VEGFR2 Pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
exact match
https://identifiers.org/reactome:R-HSA-5218804
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
has part(s)
ATP(4-)
quantity
2
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
MAP kinase p38 (Mg2+ cofactor) [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
ADP(3-)
quantity
2
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
Phospho-MAP kinase p38 (Mg2+ cofactor) [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
cites work
Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
Identifiers
Reactome ID
R-HSA-5218804
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5218804
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