(Q50313086)

2 March 2018

title

A novel approach for characterization of cathepsin D protease and its effect on tau and β-amyloid proteins. (English)

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2 March 2018

author

Guang Gary Wen

4

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2 March 2018

author name string

Mazhar Malik

1

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2 March 2018

Michael D Fenko

2

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2 March 2018

Ashfaq M Sheikh

3

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2 March 2018

Xiaohong Li

5

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2 March 2018

publication date

26 January 2011

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2 March 2018

published in

Neurochemical Research

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2 March 2018

volume

36

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2 March 2018

issue

5

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2 March 2018

page(s)

754-760

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2 March 2018

https://scigraph.springernature.com/pub.10.1007/s11064-010-0395-9

exact match

0 references

cites work

Immunolocalization of cathepsin D in normal and neoplastic human tissues

1 reference

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Cathepsin D--many functions of one aspartic protease

21 January 2018

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Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

21 January 2018

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Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

21 January 2018

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Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy

21 January 2018

1 reference

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Secretion of cytokines in breast cancer cells: the molecular mechanism of procathepsin D proliferative effects

21 January 2018

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New insights into the roles of endolysosomal cathepsins in the pathogenesis of Alzheimer's disease: cathepsin inhibitors as potential therapeutics

21 January 2018

1 reference

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Cathepsin D activity protects against development of type AA amyloid fibrils

21 January 2018

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Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects

21 January 2018

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Microtubule Assembly in the Absence of Added Nucleotides

21 January 2018

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Proteolysis of microtubule-associated protein 2 and tubulin by cathepsin D.

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21 January 2018

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A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

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In vitro processing of amyloid precursor protein by cathepsin D.

21 January 2018

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Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

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Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

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Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease

21 January 2018

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Novel cathepsin D inhibitors block the formation of hyperphosphorylated tau fragments in hippocampus.

21 January 2018

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Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein-overexpressing mice without altering behaviorally-correlated sharp wave-ripple complexes

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Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.

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Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

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Cathepsin D expression is decreased in Alzheimer's disease fibroblasts

21 January 2018

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Degradation of tau by lysosomal enzyme cathepsin D: implication for Alzheimer neurofibrillary degeneration.

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Genetic aspects of amyloid beta-protein fibrillogenesis in Alzheimer's disease

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Amyloid precursor protein gene mutations responsible for early-onset autosomal dominant Alzheimer's disease.

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Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

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The distribution of cathepsin D in rat tissues determined by immunocytochemistry

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12 December 2020

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979.

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Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

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10.1007/S11064-010-0395-9

Identifiers

DOI

1 reference

2 March 2018

1 reference

2 March 2018