(Q50315378)

2 March 2018

title

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells. (English)

1 reference

2 March 2018

19

Michael Bachmann

1 reference

2 March 2018

Jörg Steinbach

18

Jörg Steinbach

1 reference

2 March 2018

Carsten Werner

16

Carsten Werner

1 reference

2 March 2018

Martin Bornhäuser

14

Martin Bornhäuser

1 reference

2 March 2018

Gerhard Ehninger

13

Gerhard Ehninger

1 reference

2 March 2018

Petra B. Welzel

8

Petra Welzel

1 reference

2 March 2018

Anja Feldmann

4

Anja Feldmann

1 reference

2 March 2018

Claudia Arndt

6

Claudia Arndt

1 reference

2 March 2018

Stefanie Koristka

5

Stefanie Koristka

1 reference

2 March 2018

Alexandra Kegler

10

Alexandra Kegler

1 reference

2 March 2018

Armin Ehninger

11

Armin Ehninger

1 reference

2 March 2018

Susann Albert

9

Susann Albert

1 reference

2 March 2018

Dominik Bachmann

1

Dominik Bachmann

1 reference

2 March 2018

Simon Loff

7

Simon Loff

1 reference

2 March 2018

Roberta Aliperta

2

Roberta Aliperta

1 reference

2 March 2018

Jens Pietzsch

17

Jens Pietzsch

1 reference

2 March 2018

Malte von Bonin

15

Malte von Bonin

1 reference

2 March 2018

author name string

Ralf Bergmann

3

1 reference

2 March 2018

Marc Cartellieri

12

1 reference

2 March 2018

language of work or name

English

0 references

publication date

21 December 2017

1 reference

2 March 2018

published in

Oncotarget

1 reference

2 March 2018

volume

9

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2 March 2018

issue

7

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2 March 2018

page(s)

7487-7500

1 reference

2 March 2018

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology "UniCAR".

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CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia

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GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade

22 May 2018

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Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies

22 May 2018

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Versatile strategy for controlling the specificity and activity of engineered T cells

22 May 2018

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CD19-Targeted CAR T Cells: A New Tool in the Fight against B Cell Malignancies

22 May 2018

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Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110

22 May 2018

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22 May 2018

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CAR therapy: the CD19 paradigm

22 May 2018

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Adoptive therapy with CAR redirected T cells: the challenges in targeting solid tumors

22 May 2018

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CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia

22 May 2018

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Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

22 May 2018

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Simultaneous targeting of prostate stem cell antigen and prostate-specific membrane antigen improves the killing of prostate cancer cells using a novel modular T cell-retargeting system

22 May 2018

1 reference

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A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells

22 May 2018

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Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system

22 May 2018

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Retargeting of regulatory T cells to surface-inducible autoantigen La/SS-B.

22 May 2018

1 reference

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Antitumor activities of PSMA×CD3 diabodies by redirected T-cell lysis of prostate cancer cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Generation of single-chain bispecific green fluorescent protein fusion antibodies for imaging of antibody-induced T cell synapses

22 May 2018

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Inducible apoptosis as a safety switch for adoptive cell therapy

22 May 2018

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A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells

22 May 2018

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Retargeting of T cells to prostate stem cell antigen expressing tumor cells: comparison of different antibody formats

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Chimeric antigen receptor-engineered T cells for immunotherapy of cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

22 May 2018

1 reference

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Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells

22 May 2018

1 reference

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Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation

22 May 2018

1 reference

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An inducible caspase 9 safety switch for T-cell therapy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Phase 1 Dose Escalation Study of MEDI-565, a Bispecific T-Cell Engager that Targets Human Carcinoembryonic Antigen, in Patients With Advanced Gastrointestinal Adenocarcinomas.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Macroporous starPEG-heparin cryogels.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Identification of La ribonucleoproteins as a component of interchromatin granules

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Redirection of T cells with a first fully humanized bispecific CD33–CD3 antibody efficiently eliminates AML blasts without harming hematopoietic stem cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800918

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

30 November 2018

1 reference

12 December 2020

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

1 reference

12 December 2020

Simultaneous engagement of the activatory receptors NKG2D and CD3 for retargeting of effector cells to CD33-positive malignant cells

1 reference

12 December 2020

Novel humanized and highly efficient bispecific antibodies mediate killing of prostate stem cell antigen-expressing tumor cells by CD8+ and CD4+ T cells

1 reference

12 December 2020

10.18632/ONCOTARGET.23556

Identifiers

DOI

0 references

PMCID

5800918

1 reference

2 March 2018