(Q50336972)

English

Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.

scientific article published in August 2014

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854174%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization (English)

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19 March 2020

Kylie M. Wagstaff

2

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19 March 2020

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19 March 2020

Katarzyna Gajewska

4

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19 March 2020

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19 March 2020

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Anette Szczepny

1

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19 March 2020

Manisha Dias

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19 March 2020

Chunxiao Wang

5

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19 March 2020

Rebecca G Davies

6

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19 March 2020

Gurpreet Kaur

7

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19 March 2020

Jennifer Ly-Huynh

8

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19 March 2020

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publication date

1 August 2014

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19 March 2020

number of pages

8

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Biochemical Journal

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19 March 2020

461

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19 March 2020

3

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19 March 2020

469-476

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19 March 2020

The Hedgehog response network: sensors, switches, and routers

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Hedgehog signaling in development and cancer.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Gli proteins in development and disease

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

GLI transcription factors: mediators of oncogenic Hedgehog signalling

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Importin α: a multipurpose nuclear-transport receptor

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Regulation of nuclear transport: central role in development and transformation?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Targeted delivery to the nucleus.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Importins and beyond: non-conventional nuclear transport mechanisms

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

The role of Ran in nuclear function.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Role of prodomain in importin-mediated nuclear localization and activation of caspase-2

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Dynein light chain association sequences can facilitate nuclear protein import

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Apoptin nuclear accumulation is modulated by a CRM1-recognized nuclear export signal that is active in normal but not in tumor cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

HIV-1 integrase is capable of targeting DNA to the nucleus via an importin alpha/beta-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Novel properties of the nucleolar targeting signal of human angiogenin

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Impaired nuclear import and viral incorporation of Vpr derived from a HIV long-term non-progressor

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Intramolecular masking of nuclear localization signals: analysis of importin binding using a novel AlphaScreen-based method.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Gli regulation by the opposing activities of fused and suppressor of fused

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Mechanism of microtubule-facilitated "fast track" nuclear import

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Dual nuclear import mechanisms of sex determining factor SRY: intracellular Ca2+ as a switch

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Global enhancement of nuclear localization-dependent nuclear transport in transformed cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Importin alpha mRNAs have distinct expression profiles during spermatogenesis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Expression of nuclear transport importins beta 1 and beta 3 is regulated during rodent spermatogenesis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: upregulation in transgenic mice blocks spermatogenesis in pachytene

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

The C-terminus of apoptin represents a unique tumor cell-enhanced nuclear targeting module

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130709

21 January 2018

Identifiers

10.1042/BJ20130709

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854174%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854174%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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