(Q50431784)

13 March 2018

title

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. (English)

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13 March 2018

author

François Paquet-Durand

6

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13 March 2018

Susanne Feil

7

object named as

Susanne Feil

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13 March 2018

author name string

Mirko Jaumann

1

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13 March 2018

Juliane Dettling

2

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13 March 2018

Martin Gubelt

3

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13 March 2018

Ulrike Zimmermann

4

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13 March 2018

Andrea Gerling

5

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13 March 2018

Stephan Wolpert

8

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13 March 2018

Christoph Franz

9

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13 March 2018

Ksenya Varakina

10

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13 March 2018

Hao Xiong

11

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13 March 2018

Niels Brandt

12

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13 March 2018

Stephanie Kuhn

13

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13 March 2018

Hyun-Soon Geisler

14

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13 March 2018

Karin Rohbock

15

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13 March 2018

Peter Ruth

16

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13 March 2018

Jens Schlossmann

17

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13 March 2018

Joachim Hütter

18

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13 March 2018

Peter Sandner

19

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13 March 2018

Robert Feil

20

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13 March 2018

Jutta Engel

21

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13 March 2018

Marlies Knipper

22

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13 March 2018

Lukas Rüttiger

23

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13 March 2018

language of work or name

English

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publication date

22 January 2012

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13 March 2018

published in

Nature Medicine

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13 March 2018

volume

18

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13 March 2018

page(s)

252-259

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13 March 2018

issue

2

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13 March 2018

https://scigraph.springernature.com/pub.10.1038/nm.2634

exact match

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Two classes of outer hair cells along the tonotopic axis of the cochlea

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Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling

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Single-neuron labeling and chronic cochlear pathology. III. Stereocilia damage and alterations of threshold tuning curves

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Noise induces up-regulation of P2X2 receptor subunit of ATP-gated ion channels in the rat cochlea

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Distribution of IRAG and cGKI-isoforms in murine tissues

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A mechanism for sensing noise damage in the inner ear.

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Expression of a potassium current in inner hair cells during development of hearing in mice.

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Thyroid hormone receptors TRalpha1 and TRbeta differentially regulate gene expression of Kcnq4 and prestin during final differentiation of outer hair cells.

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Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells

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Effects of chronic cochlear de-efferentation on auditory-nerve response.

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Cav1.3 (α1D) Ca2+ Currents in Neonatal Outer Hair Cells of Mice

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Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.

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cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium

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Molecular properties and biological functions of cGMP-dependent protein kinase II.

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Sudden hearing loss from PDE-5 inhibitors: A possible cellular stress etiology

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Function of cGMP-dependent protein kinases as revealed by gene deletion.

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Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells

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Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss

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Expression of the P2X(2) receptor subunit of the ATP-gated ion channel in the cochlea: implications for sound transduction and auditory neurotransmission.

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12 December 2020

Expression of an inwardly rectifying K(+) channel, Kir4.1, in satellite cells of rat cochlear ganglia

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Involvement of the nitric oxide-cyclic GMP pathway and neuronal nitric oxide synthase in ATP-induced Ca2+ signalling in cochlear inner hair cells

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Thyroid hormone deficiency before the onset of hearing causes irreversible damage to peripheral and central auditory systems.

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Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness

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Identification of the amino acid sequences responsible for high affinity activation of cGMP kinase Ialpha.

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Substrate- and kinase-directed regulation of phosphorylation of a cGMP-binding phosphodiesterase by cGMP.

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Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss

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Activation of JNK in the inner ear following impulse noise exposure.

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Glucocorticoid receptor and mitogen-activated protein kinase activity after restraint stress and acoustic trauma.

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Poly(ADP-ribosyl)ation in mammalian ageing

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Nitric oxide inhibits adenosine 5'-triphosphate-induced Ca2+ response in inner hair cells of the guinea pig cochlea

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Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

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The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1

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Efficacy and safety of tadalafil once daily in the treatment of men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: results of an international randomized, double-blind, placebo-controlled trial

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ATP activates non-selective cation channels and calcium release in inner hair cells of the guinea-pig cochlea.

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Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells

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Development of the inner ear of the mouse: a radioautographic study of terminal mitoses

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12 December 2020

The commonly used cGMP-dependent protein kinase type I (cGKI) inhibitor Rp-8-Br-PET-cGMPS can activate cGKI in vitro and in intact cells

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12 December 2020

High dosage sildenafil induces hearing impairment in mice

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12 December 2020

Changes of hair cell stereocilia and threshold shift after acoustic trauma in guinea pigs: comparison between inner and outer hair cells

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12 December 2020

Phosphodiesterase type 5 inhibitor use and hearing impairment

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12 December 2020

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12 December 2020

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12 December 2020

Activation of Mitogen-activated Protein Kinase Pathways by Cyclic GMP and Cyclic GMP-dependent Protein Kinase in Contractile Vascular Smooth Muscle Cells

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12 December 2020

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12 December 2020

L-type voltage-gated calcium channel is involved in the pathogenesis of acoustic injury in the cochlea.

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12 December 2020

Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells.

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12 December 2020

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12 December 2020

Single-neuron labeling and chronic cochlear pathology. II. Stereocilia damage and alterations of spontaneous discharge rates

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12 December 2020

Role of nitric oxide on ATP-induced Ca2+ signaling in outer hair cells of the guinea pig cochlea

1 reference

12 December 2020

Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat

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12 December 2020

Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse

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12 December 2020

Functional cGMP-dependent protein kinase is phosphorylated in its catalytic domain at threonine-516.

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12 December 2020

Identifiers

DOI

10.1038/NM.2634

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13 March 2018

PubMed ID

22270721

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13 March 2018