(Q50436260)

14 March 2018

title

Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation (English)

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14 March 2018

main subject

chronic myeloid leukemia

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1

Yusuf Baran

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14 March 2018

Jacek Bielawski

2

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14 March 2018

Ufuk Gunduz

series ordinal

3

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14 March 2018

Besim Ogretmen

series ordinal

4

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14 March 2018

publication date

11 August 2011

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14 March 2018

Journal of Cancer Research and Clinical Oncology

published in

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14 March 2018

volume

137

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14 March 2018

issue

10

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14 March 2018

page(s)

1535-1544

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14 March 2018

Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

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1 reference

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12 December 2020

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Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

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12 December 2020

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12 December 2020

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells

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12 December 2020

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

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12 December 2020

Synergistic effect of imatinib mesylate and fludarabine combination on Philadelphia chromosome-positive chronic myeloid leukemia cell lines

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12 December 2020

1-phenyl-2-decanoylamino-3-morpholino-1-propanol chemosensitizes neuroblastoma cells for taxol and vincristine.

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12 December 2020

Imatinib mesylate and the management of chronic myeloid leukemia (CML)

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12 December 2020

SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells

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12 December 2020

Apoptosis induced by N-hexanoylsphingosine in CHP-100 cells associates with accumulation of endogenous ceramide and is potentiated by inhibition of glucocerebroside synthesis

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12 December 2020

Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance.

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12 December 2020

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

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12 December 2020

Resistance to imatinib: mechanisms and management

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12 December 2020

Diversity and complexity of ceramide signalling in apoptosis

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12 December 2020

10.1007/S00432-011-1016-Y

Identifiers

DOI

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14 March 2018

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14 March 2018