(Q50478273)

14 March 2018

title

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease. (English)

1 reference

14 March 2018

author

Hirokazu Hirai

7

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14 March 2018

Nicole Déglon

8

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14 March 2018

Luis Pereira De Almeida

9

1 reference

14 March 2018

Ana Vasconcelos-Ferreira

Ana Vasconcelos-Ferreira

3

0 references

Isabel Onofre

Isabel Onofre

4

0 references

Célia Aveleira

Célia Aveleira

6

0 references

Clévio Nóbrega

Clévio Nóbrega

2

0 references

David Albuquerque

David Albuquerque

5

0 references

author name string

Isabel Nascimento-Ferreira

1

1 reference

14 March 2018

language of work or name

English

0 references

publication date

1 July 2013

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14 March 2018

published in

Brain

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14 March 2018

volume

136

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14 March 2018

issue

Pt 7

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14 March 2018

page(s)

2173-2188

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14 March 2018

Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease

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1 reference

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Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells

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Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3

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Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.

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A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.

21 January 2018

1 reference

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Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells

21 January 2018

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Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

21 January 2018

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Regulation of amyloid precursor protein processing by the Beclin 1 complex

21 January 2018

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CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

21 January 2018

1 reference

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Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

21 January 2018

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Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease

21 January 2018

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21 January 2018

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21 January 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

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Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.

21 January 2018

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21 January 2018

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21 January 2018

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Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases

21 January 2018

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Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

21 January 2018

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Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.

21 January 2018

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Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins

21 January 2018

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21 January 2018

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

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Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells

21 January 2018

1 reference

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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

21 January 2018

1 reference

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Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWT144

1 reference

14 March 2018

release_bjb32phmobdtviglcembzkh4ae

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bjb32phmobdtviglcembzkh4ae

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 March 2018