(Q50481937)

English

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses.

scientific article published on 18 August 2017

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scholarly article

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/28932640

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses. (English)

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/28932640

1 reference

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inferred from title

11

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14 June 2020

Caroline Aspord

4

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14 June 2020

Stephanie Corgnac

5

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14 June 2020

Laurence Chaperot

9

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14 June 2020

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14 June 2020

Christelle Faveeuw

14

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14 June 2020

Fathia Mami-Chouaib

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Fathia Mami-Chouaib

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14 June 2020

author name string

Reem Ghinnagow

1

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14 June 2020

Julie De Meester

2

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14 June 2020

Luis Javier Cruz

3

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14 June 2020

Elodie Macho-Fernandez

6

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14 June 2020

Daphnée Soulard

7

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14 June 2020

Josette Fontaine

8

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14 June 2020

Joel Plumas

13

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14 June 2020

François Trottein

15

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14 June 2020

publication date

18 August 2017

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/28932640

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28932640%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

6

1 reference

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14 June 2020

9

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14 June 2020

e1339855

1 reference

Europe PubMed Central

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14 June 2020

Efficient Regeneration of Human Vα24+ Invariant Natural Killer T Cells and Their Anti-Tumor Activity In Vivo.

1 reference

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8 September 2018

Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8(+) T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cells

1 reference

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Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses

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Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells.

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8 September 2018

Co-operation of α-galactosylceramide-loaded tumour cells and TLR9 agonists induce potent anti-tumour responses in a murine colon cancer model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599097

8 September 2018

Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression

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8 September 2018

IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset

1 reference

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Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells

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8 September 2018

Targeted delivery of α-galactosylceramide to CD8α+ dendritic cells optimizes type I NKT cell-based antitumor responses

1 reference

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Harnessing Human Cross-Presenting CLEC9A(+)XCR1(+) Dendritic Cells for Immunotherapy

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Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.

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Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.

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The ratios of CD8+ T cells to CD4+CD25+ FOXP3+ and FOXP3- T cells correlate with poor clinical outcome in human serous ovarian cancer.

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Oncology meets immunology: the cancer-immunity cycle

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Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines

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Dendritic cell-based nanovaccines for cancer immunotherapy

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Immune system targeting by biodegradable nanoparticles for cancer vaccines

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8 September 2018

Cytotoxic and proinflammatory CD8+ T lymphocytes promote development of vulnerable atherosclerotic plaques in apoE-deficient mice

1 reference

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8 September 2018

Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions

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Consequences of direct and indirect activation of dendritic cells on antigen presentation: functional implications and clinical considerations

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From crucial to negligible: functional CD8⁺ T-cell responses and their dependence on CD4⁺ T-cell help

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Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivo

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8 September 2018

NKT-cell-based immunotherapies in clinical trials.

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Multimodal imaging of nanovaccine carriers targeted to human dendritic cells

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Harnessing natural killer T (NKT) cells in human myeloma: progress and challenges

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Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection.

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Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

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CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.

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Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein

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Loss of IFN-gamma production by invariant NK T cells in advanced cancer.

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21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/28932640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/28932640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/28932640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/2162402X.2017.1339855

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28932640%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28932640%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28932640%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

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