(Q50489935)

English

Korean red ginseng extract prevents APAP-induced hepatotoxicity through metabolic enzyme regulation: the role of ginsenoside Rg3, a protopanaxadiol.

scientific article published on 10 June 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

Korean red ginseng extract prevents APAP-induced hepatotoxicity through metabolic enzyme regulation: the role of ginsenoside Rg3, a protopanaxadiol. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

ginsenoside Rg3

1 reference

ChEBI release 2020-05-28

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based on heuristic

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author name string

Sang Il Gum

1

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

Min Kyung Cho

2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

publication date

10 June 2013

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

Liver International

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

33

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

7

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

1071-1084

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

Trends in ginseng research in 2010.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Pharmacology of ginsenosides: a literature review

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

The potent protective effect of wild ginseng (Panax ginseng C.A. Meyer) against benzo[alpha]pyrene-induced toxicity through metabolic regulation of CYP1A1 and GSTs.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Asian ginseng enhances the anti-proliferative effect of 5-fluorouracil on human colorectal cancer: comparison between white and red ginseng.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Comparison of oral and i.v. acetylcysteine in the treatment of acetaminophen poisoning

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

The ginsenoside-Rb2 lowers cholesterol and triacylglycerol levels in 3T3-L1 adipocytes cultured under high cholesterol or fatty acids conditions

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Modulating angiogenesis: the yin and the yang in ginseng

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Ginsenoside Rg3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Hepatocyte growth factor activates CCAAT enhancer binding protein and cell replication via PI3-kinase pathway

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

PI3K, RSK, and mTOR signal networks for the GST gene regulation

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Acute versus chronic alcohol consumption in acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Acetaminophen-glutathione conjugate formation in a coupled cytochrome P-450-glutathione S-transferase assay system mediated by subcellular preparations from adult and weanling rat tissues

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Genetic analysis of cytoprotective functions supported by graded expression of Keap1

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

CCAAT/enhancer-binding proteins: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Antioxidant-induced nuclear translocation of CCAAT/enhancer-binding protein beta. A critical role for protein kinase A-mediated phosphorylation of Ser299.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Activation of CCAAT/enhancer-binding protein beta by 2'-amino-3'-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12046

21 January 2018

Identifiers

10.1111/LIV.12046

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/23750847

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