(Q50501834)

14 March 2018

title

Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1. (English)

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14 March 2018

author

Evan Ingley

10

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14 March 2018

Neli S Slavova-Azmanova

object named as

Neli S Slavova-Azmanova

8

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Terrence D. Mulhern

object named as

Terrence D Mulhern

9

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Natalie J Gunn

object named as

Natalie J Gunn

7

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author name string

Rhiannon J Whiting

1

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14 March 2018

Christine J Payne

2

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14 March 2018

Jiulia Satiaputra

3

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14 March 2018

Nicole Kucera

4

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14 March 2018

Theresa W Qiu

5

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14 March 2018

Sevgi Irtegun

6

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14 March 2018

language of work or name

English

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publication date

1 March 2012

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14 March 2018

published in

Biochemical Journal

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14 March 2018

volume

442

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14 March 2018

issue

3

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14 March 2018

page(s)

611-620

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14 March 2018

Src family kinases, key regulators of signal transduction

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1 reference

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BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

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Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases

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Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

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Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts

21 January 2018

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Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.

21 January 2018

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Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling

21 January 2018

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Functional analysis of Csk and CHK kinases in breast cancer cells.

21 January 2018

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Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts

21 January 2018

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Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

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Src family kinases: regulation of their activities, levels and identification of new pathways

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

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Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

21 January 2018

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The SOCS box: a tale of destruction and degradation

21 January 2018

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Csk-binding protein can regulate Lyn signals controlling cell morphology

21 January 2018

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A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation

21 January 2018

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Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

21 January 2018

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HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells

21 January 2018

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Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells.

21 January 2018

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A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit

21 January 2018

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

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The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity

21 January 2018

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Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase.

21 January 2018

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Engineering of the Escherichia coli Im7 immunity protein as a loop display scaffold

21 January 2018

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Domain organization of the monomeric form of the Tom70 mitochondrial import receptor

21 January 2018

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Low free energy cost of very long loop insertions in proteins

21 January 2018

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Stability and peptide binding specificity of Btk SH2 domain: molecular basis for X-linked agammaglobulinemia

21 January 2018

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Alternative Modes of Tyrosyl Phosphopeptide Binding to a Src Family SH2 Domain: Implications for Regulation of Tyrosine Kinase Activity†

21 January 2018

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Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry

21 January 2018

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Targeting Src in breast cancer

21 January 2018

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SRC family kinase activity is up-regulated in hormone-refractory prostate cancer.

21 January 2018

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Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway

21 January 2018

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Nonreceptor tyrosine kinases in prostate cancer

21 January 2018

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Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells

21 January 2018

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Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase

21 January 2018

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Hydrogen Exchange Shows Peptide Binding Stabilizes Motions in Hck SH2†

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111485

21 January 2018

Identifiers

DOI

10.1042/BJ20111485

1 reference

14 March 2018

1 reference

14 March 2018