(Q50510804)

14 March 2018

title

Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo. (English)

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14 March 2018

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M Tanemura

1

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14 March 2018

Y Ohmura

2

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14 March 2018

T Deguchi

3

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14 March 2018

T Machida

4

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14 March 2018

R Tsukamoto

5

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14 March 2018

H Wada

6

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14 March 2018

S Kobayashi

7

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14 March 2018

S Marubashi

8

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14 March 2018

H Eguchi

9

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14 March 2018

T Ito

10

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14 March 2018

H Nagano

11

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14 March 2018

M Mori

12

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14 March 2018

Y Doki

13

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14 March 2018

language of work or name

English

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publication date

3 October 2011

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14 March 2018

American Journal of Transplantation

published in

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14 March 2018

volume

12

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14 March 2018

page(s)

102-114

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14 March 2018

issue

1

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14 March 2018

Development by self-digestion: molecular mechanisms and biological functions of autophagy

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Methods in mammalian autophagy research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

The role of autophagy during the early neonatal starvation period

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy genes in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

The pleiotropic role of autophagy: from protein metabolism to bactericide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Use of sirolimus in solid organ transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Molecular actions of sirolimus: sirolimus and mTor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Upstream and downstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

TOR, a central controller of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Insulin independence following isolated islet transplantation and single islet infusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Sirolimus and islet transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Five-year follow-up after clinical islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

In vivo effect of FK506 on human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Hepatocyte Growth Factor Gene Therapy for Pancreatic Islets in Diabetes: Reducing the Minimal Islet Transplant Mass Required in a Glucocorticoid-Free Rat Model of Allogeneic Portal Vein Islet Transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Rapamycin impairs in vivo proliferation of islet beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Rescue purification maximizes the use of human islet preparations for transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Improved human islet isolation using nicotinamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Improved islet yield and function with ductal injection of University of Wisconsin solution before pancreas preservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Evaluating the glucose tolerance test in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

The role of autophagy in pancreatic beta-cell and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Structure and functions of the 20S and 26S proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy in human type 2 diabetes pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy in health and disease: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy in health and disease. 4. The role of pancreatic beta-cell autophagy in health and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Targeting apoptotic and autophagic pathways for cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

Autophagy and the pancreatic beta-cell in human type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2011.03771.X

10.1111/J.1600-6143.2011.03771.X

21 January 2018

Identifiers

DOI

1 reference

14 March 2018

PubMed ID

21966953

1 reference

14 March 2018