(Q50573740)

15 March 2018

title

Structural effects on the phosphorylation of 3-substituted 1-beta-D-ribofuranosyl-1,2,4-triazoles by human adenosine kinase. (English)

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15 March 2018

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Sidath C Kumarapperuma

1

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15 March 2018

Yanjie Sun

2

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15 March 2018

Marjan Jeselnik

3

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15 March 2018

Kiwon Chung

4

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15 March 2018

William B Parker

5

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15 March 2018

Colleen B Jonsson

6

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15 March 2018

Jeffrey B Arterburn

7

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15 March 2018

language of work or name

English

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publication date

12 March 2007

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15 March 2018

number of pages

5

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Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

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15 March 2018

volume

17

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15 March 2018

issue

11

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15 March 2018

page(s)

3203-3207

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15 March 2018

Recent highlights in the development of new antiviral drugs

cites work

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12 December 2020

A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

1 reference

12 December 2020

Nuclear magnetic resonance studies of the solution properties of the antiviral nucleoside, 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, the corresponding 5'-phosphate, and related triazole nucleosides

1 reference

12 December 2020

Metabolism of 5-amino-1-β-d-ribofuranosyl- imidazole-4-carboxamide and related five-membered heterocycles to 5′-triphosphates in human blood and L5178Y cells

1 reference

12 December 2020

Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug

1 reference

12 December 2020

Respiratory syncytial virus infections: characteristics and treatment

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12 December 2020

Chemical synthesis of the 1,2,4-triazole nucleosides related to uridine, 2'-deoxyuridine, thymidine, and cytidine

1 reference

12 December 2020

Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase

1 reference

12 December 2020

Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety

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12 December 2020

Ribavirin causes error catastrophe during Hantaan virus replication.

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12 December 2020

The anti-yellow fever virus activity of ribavirin is independent of error-prone replication

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12 December 2020

Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA.

1 reference

12 December 2020

Synthesis and antiviral evaluation of N-carboxamidine-substituted analogues of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride

1 reference

12 December 2020

Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile.

1 reference

12 December 2020

Hematologic side effects of interferon and ribavirin therapy

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12 December 2020

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

1 reference

12 December 2020

Structure of human adenosine kinase at 1.5 A resolution

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12 December 2020

Sindbis virus mutants resistant to mycophenolic acid and ribavirin

1 reference

12 December 2020

Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area.

1 reference

12 December 2020

Treating HCV with ribavirin analogues and ribavirin-like molecules

1 reference

12 December 2020

Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate

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12 December 2020

Antiviral therapy targeting viral polymerase

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12 December 2020

Antiviral therapy: current concepts and practices

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12 December 2020

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

1 reference

12 December 2020

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

1 reference

12 December 2020

Adenosine kinase from rabbit liver. II. Substrate and inhibitor specificity

1 reference

12 December 2020

Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase

1 reference

12 December 2020

Antiviral drug discovery and development: where chemistry meets with biomedicine

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12 December 2020

Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

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12 December 2020

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

1 reference

12 December 2020

Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line

1 reference

12 December 2020

Mutations that confer resistance to mycophenolic acid and ribavirin on sindbis virus map to the nonstructural protein nsP1

1 reference

12 December 2020

Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases

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12 December 2020

Ribavirin treatment for patients with chronic hepatitis C: results of a placebo-controlled study

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12 December 2020

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

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12 December 2020

10.1016/J.BMCL.2007.03.018

Identifiers

DOI

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15 March 2018

PMC publication ID

7127453

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15 March 2018