(Q50627384)

16 March 2018

title

A novel cytostatic process enhances the productivity of Chinese hamster ovary cells. (English)

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16 March 2018

author name string

M Fussenegger

series ordinal

1

1 reference

16 March 2018

X Mazur

series ordinal

2

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16 March 2018

J E Bailey

series ordinal

3

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16 March 2018

publication date

1 September 1997

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16 March 2018

Biotechnology and Bioengineering

published in

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16 March 2018

volume

55

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16 March 2018

page(s)

927-939

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16 March 2018

issue

6

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16 March 2018

Limited periods of gene expression in immunoglobulin-synthesizing cells.

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Synthesis and secretion of light-chain immunoglobulin in two successive cycles of synchronized plasmacytoma cells

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

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Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

21 January 2018

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Foreign gene expression (beta-galactosidase) during the cell cycle phases in recombinant CHO cells

21 January 2018

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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Improved green fluorescence

21 January 2018

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Temperature control of growth and productivity in mutant Chinese hamster ovary cells synthesizing a recombinant protein

21 January 2018

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Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

21 January 2018

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21 January 2018

p53: puzzle and paradigm

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Cell-cycle-dependent protein accumulation by producer and nonproducer murine hybridoma cell lines: a population analysis

21 January 2018

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21 January 2018

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

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Cancer. p53, guardian of the genome

21 January 2018

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Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

21 January 2018

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21 January 2018

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

21 January 2018

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A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

21 January 2018

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Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

21 January 2018

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The genetic analysis of mammalian cell-cycle mutants

21 January 2018

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Growth and protein production kinetics of a murine myeloma cell line transfected with the human growth hormone gene

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

21 January 2018

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

21 January 2018

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Association of cdk2 Kinase with the Transcription Factor E2F During S Phase

21 January 2018

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Effect of cloned gene dosage on cell growth and hepatitis B surface antigen synthesis and secretion in recombinant CHO cells

21 January 2018

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

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Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

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Kinetics of recombinant immunoglobulin production by mammalian cells in continuous culture

21 January 2018

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

21 January 2018

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G1 phase progression: cycling on cue

21 January 2018

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Production of human immune interferon by recombinant mammalian cells cultivated on microcarriers

21 January 2018

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

21 January 2018

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Enhanced antibody production at slowed growth rates: experimental demonstration and a simple structured model

21 January 2018

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

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Temperature-sensitive mutant p53 (ala143) interferes transiently with DNA-synthesis and cell-cycle progression in Saos-2 cells.

21 January 2018

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

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A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

21 January 2018

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p21 is a universal inhibitor of cyclin kinases

21 January 2018

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Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

21 January 2018

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The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo

21 January 2018

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Inducible vectors for expression in mammalian cells

21 January 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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p21 inhibits cyclin shock

21 January 2018

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Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

21 January 2018

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Specific monoclonal antibody productivity and the cell cycle-comparisons of batch, continuous and perfusion cultures

21 January 2018

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Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

21 January 2018

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Changes in calmodulin and its mRNA accompany reentry of quiescent (G0) cells into the cell cycle

21 January 2018

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p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest

21 January 2018

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Chinese hamster ovary cell growth and interferon production kinetics in stirred batch culture

21 January 2018

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Protein expression in relation to the cell cycle of exponentially growing human prostatic epithelial cells

21 January 2018

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Will a twist of viral fate lead to a new cancer treatment?

21 January 2018

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Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

21 January 2018

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

21 January 2018

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A CHO strain producing high-level human IL-6 with the 3' deletion construct

21 January 2018

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10.1002/(SICI)1097-0290(19970920)55:6<927::AID-BIT10>3.0.CO;2-4

21 January 2018

Identifiers

DOI

1 reference

16 March 2018

PubMed ID

18636602

1 reference

16 March 2018