(Q50661808)

20 June 2018

title

Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma. (English)

1 reference

20 June 2018

author name string

Valentina Di Gialleonardo

1

1 reference

20 June 2018

Hannah N Aldeborgh

2

1 reference

20 June 2018

Vesselin Miloushev

3

1 reference

20 June 2018

Kelly M Folkers

4

1 reference

20 June 2018

Kristin Granlund

5

1 reference

20 June 2018

William D Tap

6

1 reference

20 June 2018

Jason S Lewis

7

1 reference

20 June 2018

Wolfgang A Weber

8

1 reference

20 June 2018

Kayvan R Keshari

9

1 reference

20 June 2018

language of work or name

English

0 references

publication date

6 April 2017

1 reference

20 June 2018

published in

Cancer Research

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20 June 2018

volume

77

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20 June 2018

issue

11

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20 June 2018

page(s)

3113-3120

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20 June 2018

High-Throughput Indirect Quantitation of 13C Enriched Metabolites Using 1H NMR.

cites work

1 reference

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22 June 2018

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Non-invasive differentiation of benign renal tumors from clear cell renal cell carcinomas using clinically translatable hyperpolarized (13)C pyruvate magnetic resonance

22 June 2018

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MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.

22 June 2018

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The use of dynamic nuclear polarization (13)C-pyruvate MRS in cancer

22 June 2018

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Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors

22 June 2018

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Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors

22 June 2018

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Regulation of mTORC1 by PI3K signaling

22 June 2018

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22 June 2018

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Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift

22 June 2018

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Outcomes in the management of adult soft tissue sarcomas.

22 June 2018

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Stand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer

22 June 2018

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

22 June 2018

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Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor

22 June 2018

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The epidemiology of sarcoma

22 June 2018

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Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions.

22 June 2018

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22 June 2018

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A role for maintenance therapy in managing sarcoma

22 June 2018

1 reference

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Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization

22 June 2018

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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

22 June 2018

1 reference

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DNP-Hyperpolarized C Magnetic Resonance Metabolic Imaging for Cancer Applications

22 June 2018

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The rapamycin-regulated gene expression signature determines prognosis for breast cancer

22 June 2018

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Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1.

22 June 2018

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[18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

Targeted profiling: quantitative analysis of 1H NMR metabolomics data

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

Genotoxic exposure is associated with alterations in glucose uptake and metabolism.

22 June 2018

1 reference

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Apoptosis and changes in glucose transport early after treatment of Morris hepatoma with gemcitabine

22 June 2018

1 reference

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Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies

22 June 2018

1 reference

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Glucose transport and apoptosis after gene therapy with HSV thymidine kinase

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5457322

10.1158/0008-5472.CAN-16-3310

14 August 2018

Identifiers

DOI

1 reference

20 June 2018

PMC publication ID

5457322

1 reference

20 June 2018

PubMed publication ID

28386017

1 reference

20 June 2018