(Q50667198)

English

Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels.

scientific article published on 13 January 2005

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

transmembrane protein

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Peter Westenskow

object named as

Peter Westenskow

2

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author name string

Guiscard Seebohm

1

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

Florian Lang

3

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

Michael C Sanguinetti

4

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

language of work or name

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publication date

13 January 2005

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

Journal of Physiology

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

563

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

Pt 2

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

359-368

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

KCNE1 binds to the KCNQ1 pore to regulate potassium channel activity

1 reference

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25 August 2018

Compound mutations: a common cause of severe long-QT syndrome

1 reference

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25 August 2018

Analysis of accessible surface of residues in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

The open pore conformation of potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution

1 reference

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25 August 2018

Energetic optimization of ion conduction rate by the K+ selectivity filter

1 reference

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25 August 2018

Dynamic interaction of S5 and S6 during voltage-controlled gating in a potassium channel

1 reference

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25 August 2018

Two open states and rate-limiting gating steps revealed by intracellular Na+ block of human KCNQ1 and KCNQ1/KCNE1 K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome

1 reference

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25 August 2018

Single-channel properties of IKs potassium channels

1 reference

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25 August 2018

Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Increase of the single-channel conductance of KvLQT1 potassium channels induced by the association with minK.

1 reference

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25 August 2018

Protein rearrangements underlying slow inactivation of the Shaker K+ channel

1 reference

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25 August 2018

Modulation of C-type inactivation by K+ at the potassium channel selectivity filter

1 reference

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25 August 2018

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

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25 August 2018

A side chain in S6 influences both open-state stability and ion permeation in a voltage-gated K+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

The conduction pore of a cardiac potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity

1 reference

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25 August 2018

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

1 reference

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25 August 2018

The inward rectification mechanism of the HERG cardiac potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

The "megaprimer" method of site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1665586

25 August 2018

Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

1 reference

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25 August 2018

Identifiers

10.1113/JPHYSIOL.2004.080887

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/15649981

ResearchGate publication ID

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