(Q50671884)

17 March 2018

title

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. (English)

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17 March 2018

systemic lupus erythematosus

main subject

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author

Juha Kere

11

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17 March 2018

Andrew Wong

14

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17 March 2018

Anna Dominiczak

19

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17 March 2018

Timothy Vyse

10

object named as

Timothy J Vyse

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17 March 2018

1

Min Ae Lee-Kirsch

1 reference

17 March 2018

Manfred Gahr

20

object named as

Manfred Gahr

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17 March 2018

author name string

Maolian Gong

2

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17 March 2018

Dipanjan Chowdhury

3

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17 March 2018

Lydia Senenko

4

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17 March 2018

Kerstin Engel

5

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17 March 2018

Young-Ae Lee

6

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17 March 2018

Udesh de Silva

7

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17 March 2018

Suzanna L Bailey

8

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17 March 2018

Torsten Witte

9

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Christiane Pfeiffer

12

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17 March 2018

Scott Harvey

13

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17 March 2018

Sari Koskenmies

15

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Oliver Hummel

16

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17 March 2018

Klaus Rohde

17

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17 March 2018

Reinhold E Schmidt

18

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17 March 2018

Thomas Hollis

21

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17 March 2018

Fred W Perrino

22

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17 March 2018

Judy Lieberman

23

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17 March 2018

Norbert Hübner

24

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17 March 2018

language of work or name

English

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publication date

29 July 2007

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17 March 2018

published in

Nature Genetics

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17 March 2018

volume

39

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17 March 2018

issue

9

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17 March 2018

page(s)

1065-1067

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17 March 2018

https://scigraph.springernature.com/pub.10.1038/ng2091

exact match

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cites work

Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases

1 reference

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

21 January 2018

1 reference

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

21 January 2018

1 reference

Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome

21 January 2018

1 reference

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

21 January 2018

1 reference

Role and fate of PML nuclear bodies in response to interferon and viral infections

21 January 2018

1 reference

The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering

21 January 2018

1 reference

When the message goes awry: disease-producing mutations that influence mRNA content and performance.

21 January 2018

1 reference

Role of viruses in systemic lupus erythematosus and Sjögren syndrome

21 January 2018

1 reference

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

1 reference

Features of systemic lupus erythematosus in Dnase1-deficient mice

21 January 2018

1 reference

Mutation of DNASE1 in people with systemic lupus erythematosus

21 January 2018

1 reference

Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

21 January 2018

1 reference

Demographic history and linkage disequilibrium in human populations

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG2091

1 reference

17 March 2018

1 reference

17 March 2018