(Q50676394)

English

The gain-of-function JAK2 V617F mutation shifts the phenotype of essential thrombocythemia and chronic idiopathic myelofibrosis to more "erythremic" and less "thrombocythemic": a molecular, histologic, and clinical study.

scientific article published in August 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

The gain-of-function JAK2 V617F mutation shifts the phenotype of essential thrombocythemia and chronic idiopathic myelofibrosis to more "erythremic" and less "thrombocythemic": a molecular, histologic, and clinical study (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

chronic idiopathic myelofibrosis

0 references

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2

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Tomasz Sacha

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Aleksander Skotnicki

6

object named as

Aleksander B Skotnicki

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Europe PubMed Central

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7 January 2020

author name string

Zbigniew Rudzki

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Anastazja Stój

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Sylwia Czekalska

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Małgorzata Wójcik

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Barbara Grabowska

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Andrzej Zduńczyk

8

1 reference

Europe PubMed Central

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7 January 2020

Jerzy Stachura

10

1 reference

Europe PubMed Central

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7 January 2020

publication date

1 August 2007

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

International Journal of Hematology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

86

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Europe PubMed Central

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7 January 2020

2

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Europe PubMed Central

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7 January 2020

130-136

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17875526%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and pathological criteria for the diagnosis of essential thrombocythemia, polycythemia vera, and idiopathic myelofibrosis (agnogenic myeloid metaplasia).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloproliferative disorders (MPD): myelofibrosis, myelosclerosis, extramedullary hematopoiesis, undifferentiated MPD, and hemorrhagic thrombocythemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical phenotype of wild-type, heterozygous, and homozygous JAK2V617F in polycythemia vera

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Philadelphia chromosome negative chronic myeloproliferative disorders: a practical overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presence of the JAK2 V617F mutation is associated with a higher haemoglobin and increased risk of thrombosis in essential thrombocythaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deciding on transplantation for myelofibrosis: setting the record straight

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and morphological criteria for the diagnosis of prefibrotic idiopathic (primary) myelofibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular classification and pathogenesis of eosinophilic disorders: 2005 update

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic myeloproliferative disorders with thrombocythemia: a comparative study of two classification systems (PVSG, WHO) on 839 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an acquired JAK2 mutation in polycythemia vera

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The diagnostic criteria of polycythaemia rubra vera

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAK2(V617F) tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: lineage specificity and clinical correlates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK2 mutation in essential thrombocythaemia: clinical associations and long-term prognostic relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis and classification of the polycythemias

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life expectancy of patients with chronic nonleukemic myeloproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis of essential thrombocythemia at platelet counts between 400 and 600x10(9)/L. Gruppo Italiano Malattie Mieloproliferative Croniche(GIMMC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A gain-of-function mutation of JAK2 in myeloproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation studies in CD3+, CD19+ and CD34+ cell fractions in myeloproliferative disorders with homozygous JAK2(V617F) in granulocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence, clinical features and outcome of essential thrombocythaemia in a well defined geographical area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic myeloproliferative diseases on a pathologist's desk--a dilemma of distinct entities versus a clinico-pathologic continuum. A descriptive study based on a material from the Polish population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of Bone Marrow Reticulin—A Normal Range

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAK2V617F tyrosine kinase mutation in myeloproliferative disorders: status report and immediate implications for disease classification and diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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