(Q50718278)

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Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors.

scientific article published on 22 August 2006

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29 December 2019

Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16926156%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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29 December 2019

Louis M. Luttrell

6

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29 December 2019

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Hesham M El-Shewy

1

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29 December 2019

Korey R Johnson

2

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29 December 2019

Mi-Hye Lee

3

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29 December 2019

Ayad A Jaffa

4

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29 December 2019

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22 August 2006

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29 December 2019

number of pages

9

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Journal of Biological Chemistry

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29 December 2019

281

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29 December 2019

42

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29 December 2019

31399-31407

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29 December 2019

Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

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21 January 2018

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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21 January 2018

The osmotic shock-induced glucose transport pathway in 3T3-L1 adipocytes is mediated by gab-1 and requires Gab-1-associated phosphatidylinositol 3-kinase activity for full activation

1 reference

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21 January 2018

Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.

1 reference

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21 January 2018

Mannose 6-phosphate receptors: new twists in the tale

1 reference

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21 January 2018

Keys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.

1 reference

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21 January 2018

Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

1 reference

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21 January 2018

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor

1 reference

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21 January 2018

Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase

1 reference

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21 January 2018

Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators

1 reference

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21 January 2018

Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma -dependent mitogen-activated protein kinase activation and growth

1 reference

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21 January 2018

Association of heterotrimeric G(i) with the insulin-like growth factor-I receptor. Release of G(betagamma) subunits upon receptor activation

1 reference

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21 January 2018

Insulin and insulin-like growth factor I receptors utilize different G protein signaling components

1 reference

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21 January 2018

Activation of a calcium-permeable cation channel CD20 expressed in Balb/c 3T3 cells by insulin-like growth factor-I.

1 reference

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21 January 2018

Insulin-induced activation of NADPH-dependent H2O2 generation in human adipocyte plasma membranes is mediated by Galphai2

1 reference

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21 January 2018

Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity.

1 reference

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21 January 2018

Transduction of receptor signals by beta-arrestins

1 reference

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21 January 2018

beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor

1 reference

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21 January 2018

β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis

1 reference

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21 January 2018

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

1 reference

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21 January 2018

Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades

1 reference

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21 January 2018

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

1 reference

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21 January 2018

Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells

1 reference

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21 January 2018

PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

1 reference

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21 January 2018

Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605339200

21 January 2018

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

1 reference

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21 January 2018

Effect of acidic phospholipids on sphingosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605339200

21 January 2018

The role of sphingosine-1-phosphate in smooth muscle contraction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605339200

21 January 2018

Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy

1 reference

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21 January 2018

Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors

1 reference

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21 January 2018

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

1 reference

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21 January 2018

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

1 reference

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21 January 2018

The mechanism of membrane targeting of human sphingosine kinase 1.

1 reference

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21 January 2018

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

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21 January 2018

Intracellular trafficking of hormone receptors

1 reference

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21 January 2018

Sphingosine 1-phosphate analogs as receptor antagonists

1 reference

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21 January 2018

The EGF receptor as central transducer of heterologous signalling systems

1 reference

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21 January 2018

Receptor tyrosine kinase-GPCR signal complexes

1 reference

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21 January 2018

Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1.

1 reference

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21 January 2018

Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells

1 reference

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21 January 2018

Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis toxin-sensitive G proteins

1 reference

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21 January 2018

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

1 reference

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21 January 2018

Proliferin Induces Endothelial Cell Chemotaxis through a G Protein-Coupled, Mitogen-Activated Protein Kinase-Dependent Pathway

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21 January 2018

Identifiers

10.1074/JBC.M605339200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16926156%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16926156%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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