(Q50886844)

English

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.

scientific article published on 17 July 2017

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714573%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714573%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

8

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25 March 2020

author name string

Kristine L Witt

1

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25 March 2020

Jui-Hua Hsieh

2

1 reference

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25 March 2020

Stephanie L Smith-Roe

3

1 reference

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25 March 2020

Menghang Xia

4

1 reference

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25 March 2020

Ruili Huang

5

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25 March 2020

Jinghua Zhao

6

1 reference

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25 March 2020

Scott S Auerbach

7

1 reference

Europe PubMed Central

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25 March 2020

Raymond R Tice

9

1 reference

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25 March 2020

publication date

17 July 2017

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25 March 2020

Environmental and Molecular Mutagenesis

1 reference

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25 March 2020

58

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25 March 2020

7

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25 March 2020

494-507

1 reference

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25 March 2020

Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Improving the human hazard characterization of chemicals: a Tox21 update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

International Conference on Harmonisation; guidance on S2(R1) Genotoxicity Testing and Data Interpretation for Pharmaceuticals intended for Human Use; availability. Notice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

P53 is transported into the nucleus via an Hsf1-dependent nuclear localization mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Use of in vitro HTS-derived concentration-response data as biological descriptors improves the accuracy of QSAR models of in vivo toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

The first 30 years of p53: growing ever more complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Vinblastine and diethylstilboestrol tested in the in vitro mammalian cell micronucleus test (MNvit) at Swansea University UK in support of OECD draft Test Guideline 487.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Transcriptional control of human p53-regulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Chromosome painting reveals specific patterns of chromosome occurrence in mitomycin C- and diethylstilboestrol-induced micronuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Isolation of DNA probes specific for rat chromosomal regions 19p, 19q and 4q and their application for the analysis of diethylstilbestrol-induced aneuploidy in binucleated rat fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Genotoxicity evaluation of estradiol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

Mechanism of genotoxicity of diethylstilbestrol in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555817

8 September 2018

The P53 pathway: what questions remain to be explored?

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

21 January 2018

Test No. 471: Bacterial Reverse Mutation Test

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

21 January 2018

17-alpha-ethinylestradiol and norgestrel in combination induce micronucleus increases and aneuploidy in human lymphocyte and fibroblast cultures

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

7 January 2021

based on heuristic

inferred from DOI database lookup

17-beta-estradiol fails to induce micronuclei in the bone marrow cells of rodents

1 reference

https://api.crossref.org/works/10.1002%2FEM.22112

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EM.22112

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714573%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714573%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714573%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

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