(Q50913128)

25 March 2018

title

The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals. (English)

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author

Yu-Qi Feng

4

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Bi-feng Yuan

5

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author name string

Hao-Ying Zhang

1

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25 March 2018

Jun Xiong

2

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Bao-Ling Qi

3

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language of work or name

English

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publication date

12 November 2015

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25 March 2018

published in

Chemical Communications

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volume

52

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issue

4

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page(s)

737-740

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Epigenetics in human disease and prospects for epigenetic therapy

cites work

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

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Sensitive and simultaneous determination of 5-methylcytosine and its oxidation products in genomic DNA by chemical derivatization coupled with liquid chromatography-tandem mass spectrometry analysis.

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Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.

21 January 2018

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5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations

21 January 2018

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DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry.

21 January 2018

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Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

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Tet-mediated formation of 5-hydroxymethylcytosine in RNA.

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Hydrophilic material for the selective enrichment of 5-hydroxymethylcytosine and its liquid chromatography-tandem mass spectrometry detection.

21 January 2018

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

21 January 2018

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5-methylcytosine and its derivatives.

21 January 2018

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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

21 January 2018

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Selective chemical labelling of 5-formylcytosine in DNA by fluorescent dyes

21 January 2018

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Determination of oxidation products of 5-methylcytosine in plants by chemical derivatization coupled with liquid chromatography/tandem mass spectrometry analysis.

21 January 2018

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Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.

21 January 2018

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Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals

21 January 2018

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

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Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase

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21 January 2018

Identifiers

DOI

10.1039/C5CC07354E

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25 March 2018