(Q50926565)

English

Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube.

scientific article published on 2 September 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube. (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

2

object named as

Elai Davicioni

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

author name string

Friedrich Graf Finckenstein

1

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Kent G Osborn

3

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Webster K Cavenee

4

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Karen C Arden

5

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Michael J Anderson

6

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

publication date

2 September 2006

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

Transgenic Research

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

15

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

5

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

595-614

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

https://scigraph.springernature.com/pub.10.1007/s11248-006-9011-9

0 references

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

1 reference

https://api.crossref.org/works/10.1007%2FS11248-006-9011-9

21 January 2018

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

1 reference

https://api.crossref.org/works/10.1007%2FS11248-006-9011-9

21 January 2018

Sensitivity and specificity of five abundance estimators for high-density oligonucleotide microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying biological themes within lists of genes with EASE

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic Myf5 or MyoD prevents the neuronal differentiation program in addition to inducing skeletal muscle differentiation, in the chick neural tube

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a hypaxial somite enhancer element regulating Pax3 expression in migrating myoblasts and characterization of hypaxial muscle Cre transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent truncus arteriosus in the Splotch mutant mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative DNA sequence elements are required to establish the pattern of Pax3 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax3 modulates expression of the c-Met receptor during limb muscle development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A crucial role for Pax3 in the development of the hypaxial musculature and the long-range migration of muscle precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax3 inhibits myogenic differentiation of cultured myoblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma using the reverse transcriptase-polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Multiplex Real-Time PCR Assay for the Detection of Gene Fusions Observed in Solid Tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeat-induced gene silencing in mammals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of Thr115 in MyoD positively regulates function in murine fibroblasts and human rhabdomyosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a lethal congenital heart defect in the splotch (Pax3) mutant mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16952014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11248-006-9011-9

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/16952014

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