(Q50930237)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16869785%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Subversion of the Bcl-2 life/death switch in cancer development and therapy (English)

1 reference

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27 December 2019

1

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27 December 2019

Andreas Strasser

3

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27 December 2019

Mark F van Delft

7

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27 December 2019

Philippe Bouillet

13

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27 December 2019

Alexander Egle

18

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27 December 2019

Suzanne Cory

22

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27 December 2019

David C Huang

2

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27 December 2019

Hamsa Puthalakath

9

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27 December 2019

Ewa Michalak

11

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27 December 2019

author name string

Willis S

4

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27 December 2019

Chen L

5

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27 December 2019

Wei A

6

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27 December 2019

Fletcher JI

8

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27 December 2019

Kuroda J

10

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27 December 2019

Kelly PN

12

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27 December 2019

Villunger A

14

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27 December 2019

O'Reilly L

15

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27 December 2019

Bath ML

16

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27 December 2019

Smith DP

17

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27 December 2019

Harris AW

19

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27 December 2019

Hinds M

20

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27 December 2019

Colman P

21

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27 December 2019

publication date

1 January 2005

1 reference

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Cold Spring Harbor Symposia on Quantitative Biology

27 December 2019

published in

1 reference

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27 December 2019

volume

70

1 reference

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27 December 2019

page(s)

469-477

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Ways of dying: multiple pathways to apoptosis.

27 December 2019

cites work

1 reference

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Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

21 January 2018

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Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs

21 January 2018

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Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

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Killing cancer cells by flipping the Bcl-2/Bax switch.

21 January 2018

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The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

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DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

21 January 2018

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Cell death: critical control points

21 January 2018

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Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

21 January 2018

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Bim is a suppressor of Myc-induced mouse B cell leukemia

21 January 2018

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Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

21 January 2018

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The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

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Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

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Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

21 January 2018

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

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The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

21 January 2018

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

The role of BH3-only proteins in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

21 January 2018

1 reference

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

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Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

21 January 2018

1 reference

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Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

21 January 2018

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Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

21 January 2018

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.009

21 January 2018

Identifiers

DOI

10.1101/SQB.2005.70.009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16869785%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference