(Q50950249)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

7

1 reference

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2 March 2020

Juliane Heide

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Ying Ke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Chai Ann Ng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Mark J Hunter

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Stefan A Mann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Adam P Hill

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

1 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

454

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

69-77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23721480%20AND%20SRC:MED&resulttype=core&format=json

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

2 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

A genetic framework for improving arrhythmia therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Screening for sudden cardiac death in the young: report from a national heart, lung, and blood institute working group

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Potassium channel ontogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

A family of potassium channel genes related to eag in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Functional characterization of the C-terminus of the human ether-à-go-go-related gene K(+) channel (HERG).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Cardiac IKr channels minimally comprise hERG 1a and 1b subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Heteromeric assembly of human ether-à-go-go-related gene (hERG) 1a/1b channels occurs cotranslationally via N-terminal interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Co-chaperone FKBP38 promotes HERG trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Hsp40 chaperones promote degradation of the HERG potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Quality control in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Mechanistic Insight into Human ether-a-go-go-related Gene (hERG) K+ Channel Deactivation Gating from the Solution Structure of the EAG Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

hERG potassium channel gating is mediated by N- and C-terminal region interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

HERG channel (dys)function revealed by dynamic action potential clamp technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

The eag domain regulates hERG channel inactivation gating via a direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Trigger-specific risk factors and response to therapy in long QT syndrome type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

Genotype-phenotype aspects of type 2 long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328

hERG K(+) channels: structure, function, and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130328