(Q33661427)

28 July 2017

title

Hsp40 chaperones promote degradation of the HERG potassium channel (English)

1 reference

28 July 2017

0 references

Valerie E Walker

1

1 reference

28 July 2017

Michael J H Wong

2

1 reference

28 July 2017

Roxana Atanasiu

3

1 reference

28 July 2017

Christine Hantouche

4

1 reference

28 July 2017

Jason C Young

5

1 reference

28 July 2017

Alvin Shrier

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

25 November 2009

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

285

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28 July 2017

issue

5

1 reference

28 July 2017

page(s)

3319-3329

1 reference

Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking

28 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.

21 June 2018

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21 June 2018

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A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

21 June 2018

1 reference

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Acid denaturation and refolding of green fluorescent protein

21 June 2018

1 reference

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Pathways of chaperone-mediated protein folding in the cytosol

21 June 2018

1 reference

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The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator

21 June 2018

1 reference

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CHIP: a link between the chaperone and proteasome systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

21 June 2018

1 reference

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21 June 2018

1 reference

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Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.

21 June 2018

1 reference

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 June 2018

1 reference

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Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block

21 June 2018

1 reference

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HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor

21 June 2018

1 reference

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The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

21 June 2018

1 reference

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Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 June 2018

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From the cradle to the grave: molecular chaperones that may choose between folding and degradation

21 June 2018

1 reference

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 June 2018

1 reference

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Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome

21 June 2018

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Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70

21 June 2018

1 reference

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Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Posttranslational quality control: folding, refolding, and degrading proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

A family of potassium channel genes related to eag in Drosophila and mammals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Mechanisms of arsenic-induced prolongation of cardiac repolarization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823420

Identification of a COOH-terminal segment involved in maturation and stability of human ether-a-go-go-related gene potassium channels

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19940115

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Defining the requirements for Hsp40 and Hsp70 in the Hsp90 chaperone pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19940115

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.024000

1 reference

28 July 2017

1 reference

28 July 2017

1 reference