(Q50954911)

10 June 2018

title

Focal Adhesion Kinase: The Reversible Molecular Mechanosensor. (English)

1 reference

10 June 2018

author

Samuel Bell

series ordinal

1

1 reference

PubMed publication ID

28591616

26 March 2018

http://europepmc.org/abstract/MED/28591616

Eugene Terentjev

series ordinal

2

1 reference

PubMed publication ID

28591616

26 March 2018

http://europepmc.org/abstract/MED/28591616

language of work or name

English

0 references

publication date

1 June 2017

1 reference

10 June 2018

published in

Biophysical Journal

1 reference

10 June 2018

volume

112

1 reference

10 June 2018

issue

11

1 reference

10 June 2018

page(s)

2439-2450

1 reference

10 June 2018

Mechanosensing Controlled Directly by Tyrosine Kinases.

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10 June 2018

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Mechanism of Focal Adhesion Kinase Mechanosensing

10 June 2018

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10 June 2018

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Tissue stiffness dictates development, homeostasis, and disease progression.

10 June 2018

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Substrate stress relaxation regulates cell spreading.

10 June 2018

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How cells feel: stochastic model for a molecular mechanosensor

10 June 2018

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Contractile fibers and catch-bond clusters: a biological force sensor?

10 June 2018

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New insights into the folding of a β-sheet miniprotein in a reduced space of collective hydrogen bond variables: application to a hydrodynamic analysis of the folding flow

10 June 2018

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Stiff collagen matrices increase tumorigenic prolactin signaling in breast cancer cells

10 June 2018

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Effect of substrate stiffness on early mouse embryo development

10 June 2018

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Extracellular-matrix tethering regulates stem-cell fate

10 June 2018

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Stability of domain structures in multi-domain proteins

10 June 2018

1 reference

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Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

10 June 2018

1 reference

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Mechanosensitive channels: what can they do and how do they do it?

10 June 2018

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Force generation, transmission, and integration during cell and tissue morphogenesis

10 June 2018

1 reference

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Latent TGF-β structure and activation

10 June 2018

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Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Forcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

The FERM domain: organizing the structure and function of FAK.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Stretch-activated ion channels: what are they?

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Demonstration of catch bonds between an integrin and its ligand.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Environmental sensing through focal adhesions

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Signal transduction by focal adhesion kinase in cancer

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Spatial and temporal regulation of focal adhesion kinase activity in living cells.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesion kinase as a regulator of cell tension in the progression of cancer

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Structural basis for the autoinhibition of focal adhesion kinase

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesion kinase: a potential target in cancer therapy

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Integrin signalling: the tug-of-war in heart hypertrophy.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Theory of force regulation by nascent adhesion sites

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesion kinase: in command and control of cell motility

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

FERM domain interaction promotes FAK signaling

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Synthetic elastin hydrogels derived from massive elastic assemblies of self-organized human protein monomers

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Adhesion-dependent cell mechanosensitivity.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesion kinase: the first ten years

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Integrins: bidirectional, allosteric signaling machines

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Myofibroblasts and mechano-regulation of connective tissue remodelling

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Elastic proteins: biological roles and mechanical properties

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Conformational spread in a ring of proteins: a stochastic approach to allostery

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Protein folding and unfolding in microseconds to nanoseconds by experiment and simulation

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

TGF-beta: from latent to active

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Heightened sensitivity of a lattice of membrane receptors

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Dynamic strength of molecular adhesion bonds

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Relationship between body mass and biomechanical properties of limb tendons in adult mammals

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Single myosin molecule mechanics: piconewton forces and nanometre steps

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Transduction of membrane tension by the ion channel alamethicin

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Integrins: versatility, modulation, and signaling in cell adhesion

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Models for the Specific Adhesion of Cells to Cells

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Intrinsic rates and activation free energies from single-molecule pulling experiments.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Stochastic dynamics of adhesion clusters under shared constant force and with rebinding.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Complexity and specificity of integrin signalling.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474844

Single-molecule rupture dynamics on multidimensional landscapes

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28591616

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Focal adhesions as mechanosensors: The two-spring model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28591616

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BPJ.2017.04.048

1 reference

10 June 2018

release_f72r7hstava65fnprwa7lccsry

1 reference

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f72r7hstava65fnprwa7lccsry

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

5474844

1 reference

10 June 2018

PubMed publication ID

28591616

1 reference

10 June 2018