(Q50990734)

English

MD2 mediates angiotensin II-induced cardiac inflammation and remodeling via directly binding to Ang II and activating TLR4/NF-κB signaling pathway.

scientific article published on 24 December 2016

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scholarly article

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

MD2 mediates angiotensin II-induced cardiac inflammation and remodeling via directly binding to Ang II and activating TLR4/NF-κB signaling pathway. (English)

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

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toll-like receptor

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author name string

Jibo Han

1

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Chunpeng Zou

2

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Liqin Mei

3

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Yali Zhang

4

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Yuanyuan Qian

5

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Shengban You

6

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Yong Pan

7

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Zheng Xu

8

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Bin Bai

9

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Weijian Huang

10

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Guang Liang

11

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

publication date

24 December 2016

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

Basic Research in Cardiology

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

112

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Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

1

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Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

9

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

https://scigraph.springernature.com/pub.10.1007/s00395-016-0599-5

0 references

HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

The war against heart failure: the Lancet lecture

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Angiotensin II-induced hypertension is modulated by nuclear factor-κBin the paraventricular nucleus.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

MD-2 binds cholesterol

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Recent Developments in Heart Failure

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Serum amyloid A3 binds MD-2 to activate p38 and NF-κB pathways in a MyD88-dependent manner.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Targeting myeloid differentiation 2 for treatment of sepsis.

1 reference

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21 January 2018

Anti-toll like receptor 4 (TLR4) therapy diminishes cardiac remodeling regardless of changes in blood pressure in spontaneously hypertensive rats (SHR).

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Immune cell and other noncardiomyocyte regulation of cardiac hypertrophy and remodeling

1 reference

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21 January 2018

Targeting of Toll-like receptors: a decade of progress in combating infectious diseases

1 reference

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21 January 2018

Cardiovascular remodelling in coronary artery disease and heart failure

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

New take on the role of angiotensin II in cardiac hypertrophy and fibrosis

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Angiotensin II facilitates fibrogenic effect of TGF-β1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Structural similarity between the hydrophobic fluorescent probe and lipid A as a ligand of MD-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

MCP-1-induced protein attenuates post-infarct cardiac remodeling and dysfunction through mitigating NF-κB activation and suppressing inflammation-associated microRNA expression.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Ventricular remodeling in heart failure with preserved ejection fraction

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Inflammatory cytokines in vascular dysfunction and vascular disease

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Involvement of tumor necrosis factor-alpha in angiotensin II-mediated effects on salt appetite, hypertension, and cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

The renin-angiotensin system and experimental heart failure

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

MD-2 is required for disulfide HMGB1-dependent TLR4 signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-016-0599-5

21 January 2018

Identifiers

10.1007/S00395-016-0599-5

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

1 reference

Europe PubMed Central

26 March 2018

http://europepmc.org/abstract/MED/28013347

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