(Q50992137)

26 March 2018

title

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation. (English)

1 reference

26 March 2018

Erb-b2 receptor tyrosine kinase 2

main subject

1 reference

David Kain

4

0 references

Mattia Lauriola

object named as

Mattia Lauriola

3

0 references

Gabriele D'Uva

object named as

Gabriele D'Uva

1

0 references

Richard P. Harvey

object named as

Richard P Harvey

19

0 references

author name string

Alla Aharonov

2

1 reference

26 March 2018

Yfat Yahalom-Ronen

5

1 reference

26 March 2018

Silvia Carvalho

6

1 reference

26 March 2018

Karen Weisinger

7

1 reference

26 March 2018

Elad Bassat

8

1 reference

26 March 2018

Dana Rajchman

9

1 reference

26 March 2018

Oren Yifa

10

1 reference

26 March 2018

Marina Lysenko

11

1 reference

26 March 2018

Tal Konfino

12

1 reference

26 March 2018

Julius Hegesh

13

1 reference

26 March 2018

Ori Brenner

14

1 reference

26 March 2018

Michal Neeman

15

1 reference

26 March 2018

Yosef Yarden

16

1 reference

26 March 2018

Jonathan Leor

17

1 reference

26 March 2018

Rachel Sarig

18

1 reference

26 March 2018

Eldad Tzahor

20

1 reference

26 March 2018

publication date

6 April 2015

1 reference

26 March 2018

published in

Nature Cell Biology

1 reference

26 March 2018

volume

17

1 reference

26 March 2018

issue

5

1 reference

26 March 2018

page(s)

627-638

1 reference

26 March 2018

https://scigraph.springernature.com/pub.10.1038/ncb3149

exact match

0 references

cites work

Evidence for cardiomyocyte renewal in humans

1 reference

Mammalian heart renewal by pre-existing cardiomyocytes

21 January 2018

1 reference

21 January 2018

Regenerating the heart

1 reference

Getting to the heart of regeneration in zebrafish.

21 January 2018

1 reference

From fish to amphibians to mammals: in search of novel strategies to optimize cardiac regeneration

21 January 2018

1 reference

Cardiac muscle regeneration: lessons from development

21 January 2018

1 reference

Cardiac stem cell therapy and the promise of heart regeneration

21 January 2018

1 reference

A proliferative burst during preadolescence establishes the final cardiomyocyte number.

21 January 2018

1 reference

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

21 January 2018

1 reference

Transient regenerative potential of the neonatal mouse heart

21 January 2018

1 reference

An emerging consensus on cardiac regeneration

21 January 2018

1 reference

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

21 January 2018

1 reference

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

21 January 2018

1 reference

Requirement for neuregulin receptor erbB2 in neural and cardiac development

21 January 2018

1 reference

Multiple essential functions of neuregulin in development

21 January 2018

1 reference

Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.

21 January 2018

1 reference

A dual role for ErbB2 signaling in cardiac trabeculation

21 January 2018

1 reference

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation

21 January 2018

1 reference

Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes

21 January 2018

1 reference

Neuregulin in cardiovascular development and disease

21 January 2018

1 reference

The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation

21 January 2018

1 reference

Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt

21 January 2018

1 reference

Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury

21 January 2018

1 reference

Neuregulin-1/ErbB signaling and chronic heart failure

21 January 2018

1 reference

The role of Neuregulin-1beta/ErbB signaling in the heart

21 January 2018

1 reference

Parenteral administration of recombinant human neuregulin‐1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses

21 January 2018

1 reference

Neuregulin-1β for the treatment of systolic heart failure

21 January 2018

1 reference

Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice.

21 January 2018

1 reference

Untangling the ErbB signalling network

21 January 2018

1 reference

EGF-ERBB signalling: towards the systems level

21 January 2018

1 reference

Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions

21 January 2018

1 reference

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

21 January 2018

1 reference

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

1 reference

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

21 January 2018

1 reference

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

21 January 2018

1 reference

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

21 January 2018

1 reference

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy

21 January 2018

1 reference

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system

21 January 2018

1 reference

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

21 January 2018

1 reference

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association

21 January 2018

1 reference

Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex

21 January 2018

1 reference

Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice

21 January 2018

1 reference

Nongenetic method for purifying stem cell-derived cardiomyocytes

21 January 2018

1 reference

Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells.

21 January 2018

1 reference

β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression.

21 January 2018

1 reference

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

Oncogene-mediated inhibition of glycogen synthase kinase 3 beta impairs degradation of prolactin receptor

21 January 2018

1 reference

ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells

21 January 2018

1 reference

p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

21 January 2018

1 reference

FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction

21 January 2018

1 reference

Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.

21 January 2018

1 reference

Cell death in the pathogenesis of heart disease: mechanisms and significance

21 January 2018

1 reference

Apoptosis in myocardial ischaemia and infarction

21 January 2018

1 reference

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

21 January 2018

1 reference

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

21 January 2018

1 reference

Macrophages are required for neonatal heart regeneration

21 January 2018

1 reference

Hippo signaling impedes adult heart regeneration.

21 January 2018

1 reference

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

21 January 2018

1 reference

Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice

21 January 2018

1 reference

Surgical models for cardiac regeneration in neonatal mice

21 January 2018

1 reference

Cyclin A2 mediates cardiomyocyte mitosis in the postmitotic myocardium

21 January 2018

1 reference

The c-myc proto-oncogene regulates cardiac development in transgenic mice

21 January 2018

1 reference

Multimodal imaging reveals a role for Akt1 in fetal cardiac development.

21 January 2018

1 reference

Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy

21 January 2018

1 reference

12 December 2020

Survey of studies examining mammalian cardiomyocyte DNA synthesis

1 reference

12 December 2020

A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure

1 reference

12 December 2020

Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development

1 reference

12 December 2020

Conditional transgene expression in the heart

1 reference

12 December 2020

Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling

1 reference

12 December 2020

The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB3149

1 reference

26 March 2018

1 reference

26 March 2018