(Q51012505)

27 March 2018

title

STAT3 is required for Flt3L-dependent dendritic cell differentiation. (English)

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27 March 2018

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Richard A Flavell

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27 March 2018

author name string

Yasmina Laouar

series ordinal

1

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27 March 2018

Thomas Welte

series ordinal

2

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27 March 2018

Xin-Yuan Fu

series ordinal

3

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27 March 2018

language of work or name

English

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publication date

1 December 2003

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27 March 2018

published in

Immunity

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27 March 2018

volume

19

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27 March 2018

issue

6

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27 March 2018

page(s)

903-912

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27 March 2018

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

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Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Selective activation of Jak2, Stat3, and Stat5b

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Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

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Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs

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The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3

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Characterization of a common precursor population for dendritic cells

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Upon dendritic cell (DC) activation chemokines and chemokine receptor expression are rapidly regulated for recruitment and maintenance of DC at the inflammatory site

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The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor

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Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

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Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

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STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

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Conditional expression of murine Flt3 ligand leads to expansion of multiple dendritic cell subsets in peripheral blood and tissues of transgenic mice

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Dendritic cell potentials of early lymphoid and myeloid progenitors

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Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

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Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential

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Role of hematopoietic growth factors/flt3 ligand in expansion and regulation of dendritic cells

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Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

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CD8 + mouse spleen dendritic cells do not originate from the CD8 - dendritic cell subset

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

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Control of myeloid-specific integrin alpha Mbeta 2 (CD11b/CD18) expression by cytokines is regulated by Stat3-dependent activation of PU.1.

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A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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Functional differences between Stat3alpha and Stat3beta

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FLT3 ligand induces the generation of functionally active dendritic cells in mice

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Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

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STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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Gene expression analysis of purified hematopoietic stem cells and committed progenitors

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Development of CD8 -Positive Dendritic Cells from a Common Myeloid Progenitor

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7 January 2021

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells

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7 January 2021

Granulocyte-macrophage colony-stimulating factor induces a unique set of STAT factors in murine dendritic cells

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7 January 2021

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

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7 January 2021

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny

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RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells

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7 January 2021

Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

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7 January 2021

10.1016/S1074-7613(03)00332-7

Identifiers

DOI

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27 March 2018

PubMed ID

14670306

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27 March 2018