(Q51036179)

English

A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions.

scientific article published on 24 September 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions. (English)

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

alcohol dependence

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based on heuristic

inferred from title

Alexander Hammers

5

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

Federico Turkheimer

8

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

David J. Brooks

9

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

object named as

David J Nutt

11

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Alastair G Reid

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

Anne Lingford-Hughes

1

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Anne Lingford-Hughes

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Europe PubMed Central

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27 March 2018

http://europepmc.org/abstract/MED/20870689

7

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Lula Rosso

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Europe PubMed Central

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27 March 2018

http://europepmc.org/abstract/MED/20870689

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Adrian Feeney

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

author name string

James Myers

3

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

Lindsay G Taylor

6

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27 March 2018

http://europepmc.org/abstract/MED/20870689

Paul Grasby

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27 March 2018

http://europepmc.org/abstract/MED/20870689

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publication date

24 September 2010

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

Journal of Psychopharmacology

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27 March 2018

http://europepmc.org/abstract/MED/20870689

26

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PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

273-281

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil.

1 reference

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Hippocampal volume in patients with alcohol dependence.

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An Inventory for Measuring Depression

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Hippocampus volume loss due to chronic heavy drinking.

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Lack of association between hippocampal volume reduction and first-onset alcohol withdrawal seizure. A volumetric MRI study

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gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions

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Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro

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Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

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Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.

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Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

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Spectral analysis of dynamic PET studies.

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Is there cognitive impairment in clinically 'healthy' abstinent alcohol dependence?

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21 January 2018

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

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21 January 2018

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

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21 January 2018

Regional variations in the effects of chronic ethanol administration on GABA(A) receptor expression: potential mechanisms

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Automatic segmentation of brain MRIs of 2-year-olds into 83 regions of interest.

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Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe

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21 January 2018

Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment

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21 January 2018

Reduced levels of GABA-benzodiazepine receptor in alcohol dependency in the absence of grey matter atrophy.

1 reference

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21 January 2018

Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography

1 reference

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21 January 2018

GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study

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21 January 2018

Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography

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21 January 2018

Decreased volume of the brain reward system in alcoholism

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21 January 2018

A high affinity ligand for GABAA-receptor containing alpha5 subunit antagonizes ethanol's neurobehavioral effects in Long-Evans rats

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21 January 2018

A widespread distinct pattern of cerebral atrophy in patients with alcohol addiction revealed by voxel-based morphometry

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21 January 2018

Assessment of spatial normalization of PET ligand images using ligand-specific templates.

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21 January 2018

Chronic ethanol administration increases the binding of the benzodiazepine inverse agonist and alcohol antagonist [3H]RO15-4513 in rat brain

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21 January 2018

Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist

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21 January 2018

Identification of neurotransmitter receptor genes involved in alcohol self-administration in the rat prefrontal cortex, hippocampus and amygdala

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21 January 2018

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

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21 January 2018

Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys

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21 January 2018

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

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21 January 2018

Memory effects of benzodiazepines: memory stages and types versus binding-site subtypes

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21 January 2018

Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking

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21 January 2018

Role of GABAA alpha5-containing receptors in ethanol reward: the effects of targeted gene deletion, and a selective inverse agonist

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Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.

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Striatal and forebrain nuclei volumes: contribution to motor function and working memory deficits in alcoholism

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Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics.

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Prenatal alcohol exposure alters GABA(A)alpha5 expression: a mechanism of alcohol-induced learning dysfunction.

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The use of spectral analysis to determine regional cerebral glucose utilization with positron emission tomography and [18F]fluorodeoxyglucose: theory, implementation, and optimization procedures

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Estimation of the number of "true" null hypotheses in multivariate analysis of neuroimaging data

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Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513

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Identifiers

10.1177/0269881110379509

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20870689

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