(Q51041590)

http://europepmc.org/abstract/MED/28431230

27 March 2018

title

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

Daan C. Swarts

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

author name string

John van der Oost

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

publication date

1 April 2017

1 reference

http://europepmc.org/abstract/MED/28431230

27 March 2018

published in

Molecular Cell

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

volume

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

page(s)

221-233.e4

1 reference

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Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells.

13 May 2020

cites work

1 reference

12 December 2020

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

1 reference

12 December 2020

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus

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12 December 2020

PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease

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Efficient genome editing in zebrafish using a CRISPR-Cas system

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12 December 2020

The Phyre2 web portal for protein modeling, prediction and analysis

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12 December 2020

CRISPR-Cas immunity in prokaryotes

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12 December 2020

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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12 December 2020

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

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12 December 2020

The Structure of Human Argonaute-2 in Complex with miR-20a

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12 December 2020

The Crystal Structure of Human Argonaute2

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12 December 2020

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

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12 December 2020

The crystal structure of Cpf1 in complex with CRISPR RNA

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12 December 2020

SOLVE and RESOLVE: automated structure solution, density modification and model building

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12 December 2020

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

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RNA-guided genetic silencing systems in bacteria and archaea

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12 December 2020

Harnessing CRISPR-Cas9 immunity for genetic engineering

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12 December 2020

Diversity and evolution of class 2 CRISPR-Cas systems

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12 December 2020

Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins.

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12 December 2020

Unravelling the structural and mechanistic basis of CRISPR-Cas systems

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12 December 2020

Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.

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12 December 2020

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

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12 December 2020

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

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12 December 2020

Detection of inosine in messenger RNA by inosine-specific cleavage.

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12 December 2020

Generation of knockout mice by Cpf1-mediated gene targeting.

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12 December 2020

Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells.

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12 December 2020

Structure of yeast Argonaute with guide RNA

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12 December 2020

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

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12 December 2020

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

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12 December 2020

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

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12 December 2020

Generation of targeted mutant rice using a CRISPR-Cpf1 system

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12 December 2020

Cas9 as a versatile tool for engineering biology

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12 December 2020

Planting the seed: target recognition of short guide RNAs.

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12 December 2020

Landscape of target:guide homology effects on Cas9-mediated cleavage

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12 December 2020

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

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12 December 2020

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA

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12 December 2020

Features and development of Coot

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12 December 2020

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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12 December 2020

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

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12 December 2020

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

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12 December 2020

Towards automated crystallographic structure refinement with phenix.refine

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12 December 2020

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

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12 December 2020

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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12 December 2020

Efficient targeted mutagenesis of rice and tobacco genomes using Cpf1 from Francisella novicida

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12 December 2020

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

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12 December 2020

Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition

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12 December 2020

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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12 December 2020

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

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12 December 2020

Erratum: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.

1 reference

12 December 2020

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

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12 December 2020

RNA-guided human genome engineering via Cas9

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12 December 2020

Phasercrystallographic software

1 reference

12 December 2020

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

1 reference

12 December 2020

Development and applications of CRISPR-Cas9 for genome engineering

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

1 reference

12 December 2020

Model morphing and sequence assignment after molecular replacement

1 reference

12 December 2020

Mechanism of RNA 2',3'-cyclic phosphate end healing by T4 polynucleotide kinase-phosphatase

1 reference

12 December 2020

RNA-programmed genome editing in human cells

1 reference

12 December 2020

CRISPR-mediated adaptive immune systems in bacteria and archaea

1 reference

12 December 2020

Deciphering key features in protein structures with the new ENDscript server

1 reference

12 December 2020

10.1016/J.MOLCEL.2017.03.016

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6879319&resulttype=core&format=json

13 May 2020

1 reference