(Q51063696)

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Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer.

scientific article published on 22 July 2014

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Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer. (English)

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Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

colorectal cancer

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Jason A. Dominitz

8

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Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

15

object named as

Douglas K Rex

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Europe PubMed Central

PubMed publication ID

28 March 2018

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James M Church

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Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

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Francis M Giardiello

1

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Europe PubMed Central

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28 March 2018

http://europepmc.org/abstract/MED/25070057

John I Allen

2

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Jennifer E Axilbund

3

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28 March 2018

http://europepmc.org/abstract/MED/25070057

C Richard Boland

4

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Carol A Burke

5

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28 March 2018

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Randall W Burt

6

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28 March 2018

http://europepmc.org/abstract/MED/25070057

David A Johnson

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Tonya Kaltenbach

10

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Theodore R Levin

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28 March 2018

http://europepmc.org/abstract/MED/25070057

David A Lieberman

12

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Douglas J Robertson

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Sapna Syngal

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28 March 2018

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22 July 2014

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28 March 2018

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The American Journal of Gastroenterology

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28 March 2018

http://europepmc.org/abstract/MED/25070057

109

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28 March 2018

http://europepmc.org/abstract/MED/25070057

8

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28 March 2018

http://europepmc.org/abstract/MED/25070057

1159-1179

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Europe PubMed Central

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28 March 2018

http://europepmc.org/abstract/MED/25070057

Cancer statistics, 2013

1 reference

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21 January 2018

Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).

1 reference

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21 January 2018

Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.

1 reference

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21 January 2018

Hereditary factors in cancer. Study of two large midwestern kindreds

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21 January 2018

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1 reference

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21 January 2018

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1 reference

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21 January 2018

Mutation of a mutL homolog in hereditary colon cancer

1 reference

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21 January 2018

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

1 reference

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21 January 2018

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

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21 January 2018

Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.

1 reference

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21 January 2018

1 reference

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21 January 2018

Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment

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21 January 2018

Cancer Risks For Mismatch Repair Gene Mutation Carriers: A Population-Based Early Onset Case-Family Study

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21 January 2018

Estimating cancer risk in HNPCC by the GRL method.

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21 January 2018

Risks of Lynch syndrome cancers for MSH6 mutation carriers

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21 January 2018

Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario

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21 January 2018

Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance

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21 January 2018

The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Feasibility of screening for Lynch syndrome among patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Clinical description of the Lynch syndrome [hereditary nonpolyposis colorectal cancer (HNPCC)].

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery

1 reference

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21 January 2018

Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Cancer risk in mutation carriers of DNA-mismatch-repair genes

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Value of MLH1 and MSH2 mutations in the appearance of Muir-Torre syndrome phenotype in HNPCC patients presenting sebaceous gland tumors or keratoacanthomas

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

The frequency of Muir-Torre syndrome among Lynch syndrome families

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

The clinical features of ovarian cancer in hereditary nonpolyposis colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Risk and epidemiological time trends of gastric cancer in Lynch syndrome carriers in the Netherlands.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Risks of less common cancers in proven mutation carriers with lynch syndrome

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Evidence for breast cancer as an integral part of Lynch syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Elevated risk of prostate cancer among men with Lynch syndrome

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Café-au-lait spots and early onset colorectal neoplasia: a variant of HNPCC?

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

The gastrointestinal phenotype of germline biallelic mismatch repair gene mutations

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X

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21 January 2018

1 reference

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21 January 2018

The molecular basis of Turcot's syndrome

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21 January 2018

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

The genetics of hereditary colon cancer

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21 January 2018

Refining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variants

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Clues to the pathogenesis of familial colorectal cancer

1 reference

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21 January 2018

Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Genetic Instability Caused by Loss of MutS Homologue 3 in Human Colorectal Cancer

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Little evidence for involvement of MLH3 in colorectal cancer predisposition

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21 January 2018

Analysis of the prostate cancer-susceptibility locus HPC20 in 172 families affected by prostate cancer

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21 January 2018

1 reference

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21 January 2018

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

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21 January 2018

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21 January 2018

Prediction of Lynch syndrome in consecutive patients with colorectal cancer

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Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy

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21 January 2018

Report from the Jerusalem workshop on Lynch syndrome-hereditary nonpolyposis colorectal cancer

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Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population.

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21 January 2018

Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

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Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer

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21 January 2018

Identification of Lynch syndrome among patients with colorectal cancer

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives

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21 January 2018

Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis

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21 January 2018

EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome

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Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center.

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Genetic testing for hereditary colorectal cancer: challenges in identifying, counseling, and managing high-risk patients

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Genetic testing for colon cancer: joint statement of the American College of Medical Genetics and American Society of Human Genetics. Joint Test and Technology Transfer Committee Working Group

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21 January 2018

American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility

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21 January 2018

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Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study

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One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome

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21 January 2018

1 reference

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21 January 2018

Impact of colonoscopic screening in male and female Lynch syndrome carriers with an MSH2 mutation

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21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

1 reference

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21 January 2018

Gynecologic screening in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Improvement of endometrial biopsy over transvaginal ultrasound alone for endometrial surveillance in women with Lynch syndrome

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Impact of gynecological screening in Lynch syndrome carriers with an MSH2 mutation

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

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A cost-effectiveness analysis of prophylactic surgery versus gynecologic surveillance for women from hereditary non-polyposis colorectal cancer (HNPCC) Families

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Cost-effectiveness analysis of prevention strategies for gynecologic cancers in Lynch syndrome.

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

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International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

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The spectrum of urological malignancy in Lynch syndrome

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Quality of life after surgery for colon cancer in patients with Lynch syndrome: partial versus subtotal colectomy

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Decision analysis in the surgical treatment of colorectal cancer due to a mismatch repair gene defect

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Risk of colonic neoplasia after proctectomy for rectal cancer in hereditary nonpolyposis colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

1 reference

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21 January 2018

Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

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Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men

1 reference

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Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

1 reference

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21 January 2018

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

No Support for Endoscopic Surveillance for Gastric Cancer in Hereditary Non-Polyposis Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Identification in Daily Practice of Patients With Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer): Revised Bethesda Guidelines-Based ApproachVersusMolecular Screening

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https://api.crossref.org/works/10.1038%2FAJG.2014.186

21 January 2018

Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study

1 reference

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21 January 2018

The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer

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21 January 2018

Identifiers

10.1038/AJG.2014.186

1 reference

Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 March 2018

http://europepmc.org/abstract/MED/25070057

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