(Q51069616)

28 March 2018

title

PKA/Smurf1 signaling-mediated stabilization of Nur77 is required for anticancer drug cisplatin-induced apoptosis. (English)

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28 March 2018

author name string

H Lin

1

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28 March 2018

Q Lin

2

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28 March 2018

M Liu

3

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28 March 2018

Y Lin

4

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28 March 2018

X Wang

5

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28 March 2018

H Chen

6

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28 March 2018

Z Xia

7

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28 March 2018

B Lu

8

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28 March 2018

F Ding

9

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28 March 2018

Q Wu

10

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28 March 2018

H-R Wang

11

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28 March 2018

language of work or name

English

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publication date

15 April 2013

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28 March 2018

published in

Oncogene

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28 March 2018

volume

33

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28 March 2018

issue

13

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28 March 2018

page(s)

1629-1639

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28 March 2018

Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease.

cites work

1 reference

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

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Targeting NR4A1 (TR3) in cancer cells and tumors

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Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis

21 January 2018

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Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms.

21 January 2018

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Early events in the induction of apoptosis in ovarian carcinoma cells by CD437: activation of the p38 MAP kinase signal pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Enrichment of Nur77 mediated by retinoic acid receptor β leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

21 January 2018

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Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.

21 January 2018

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ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3.

21 January 2018

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Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Akt phosphorylates and regulates the orphan nuclear receptor Nur77

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Phosphorylation of Nur77 by the MEK-ERK-RSK cascade induces mitochondrial translocation and apoptosis in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.

21 January 2018

1 reference

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The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling.

21 January 2018

1 reference

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p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction

21 January 2018

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Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment

21 January 2018

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Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Phosphorylation of E3 ligase Smurf1 switches its substrate preference in support of axon development

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Regulation of planar cell polarity by Smurf ubiquitin ligases

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messenger

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.116

Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Clinical development of platinum complexes in cancer therapy: an historical perspective and an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Mechanisms of resistance to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Biochemical mechanisms of cisplatin cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Molecular mechanisms of cisplatin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Degradation of RhoA by Smurf1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Nuclear orphan receptor TR3/Nur77 mediates melanoma cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.116

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.116

1 reference

28 March 2018

1 reference

28 March 2018