(Q51090801)

29 March 2018

title

Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment (English)

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29 March 2018

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Bhandoola A

1

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29 March 2018

Cibotti R

2

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29 March 2018

Punt JA

3

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29 March 2018

Granger L

4

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29 March 2018

Adams AJ

5

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29 March 2018

Sharrow SO

6

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29 March 2018

Singer A

7

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29 March 2018

language of work or name

English

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publication date

1 March 1999

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29 March 2018

published in

Immunity

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29 March 2018

volume

10

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29 March 2018

issue

3

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29 March 2018

page(s)

301-311

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29 March 2018

Delayed thymocyte development induced by augmented expression of p56lck

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The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection

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7 January 2021

Two distinct pathways of positive selection for thymocytes

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7 January 2021

Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection

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7 January 2021

Exclusion and inclusion of α and β T cell receptor alleles

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7 January 2021

Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection

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7 January 2021

Another view of the selective model of thymocyte selection

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Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

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7 January 2021

Kinetics of mature T-cell development in the thymus

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7 January 2021

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors

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7 January 2021

T cell receptor beta chain dimers on immature thymocytes from normal mice

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7 January 2021

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

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Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

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7 January 2021

Intrathymic maturation of murine T lymphocytes from CD8+ precursors

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7 January 2021

T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

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7 January 2021

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

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7 January 2021

Accessories or coreceptors?

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7 January 2021

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

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7 January 2021

Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and

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7 January 2021

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

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7 January 2021

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

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7 January 2021

Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program

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7 January 2021

Small cortical thymocytes are subject to positive selection

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7 January 2021

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

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7 January 2021

Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation

1 reference

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7 January 2021

Positive selection of thymocytes bearing alpha beta T cell receptors.

1 reference

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7 January 2021

How Many Thymocytes Audition for Selection?

1 reference

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7 January 2021

Profound block in thymocyte development in mice lacking p56lck

1 reference

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

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7 January 2021

Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4

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7 January 2021

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

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7 January 2021

Lineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis

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7 January 2021

Selective events in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

A molecular map of T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Heterogeneous expression of recombination activating genes and surface CD5 in CD3low CD4+ CD8+ thymocytes

1 reference

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7 January 2021

The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Small CD4+8+TCRlow thymocytes contain precursors of mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Post-transcriptional regulation of early T cell development by T cell receptor signals

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

A role for CD5 in TCR-mediated signal transduction and thymocyte selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Structure and function of the pre-T cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

Positive selection of immature alpha beta T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980030-8

7 January 2021

10.1016/S1074-7613(00)80030-8

Identifiers

DOI

1 reference

29 March 2018

1 reference

29 March 2018