(Q51153330)

English

The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism

scientific article published on January 14, 1992

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism (English)

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most precise value

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

The rate of formation of transition-state analogues in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1731884

11 November 2022

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

1

object named as

L. C. Kurz

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11 November 2022

4

object named as

C. Frieden

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11 November 2022

author name string

L. Moix

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1731884

11 November 2022

M. C. Riley

3

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11 November 2022

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publication date

1 January 1992

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

14 January 1992

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1731884

11 November 2022

full work available at URL

https://pubs.acs.org/doi/pdf/10.1021/bi00116a008

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

31

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

1

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

39-48

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

Deaza analogues of adenosine as inhibitors of blood platelet aggregation

1

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM--a flexible, portable system.

3

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

Possible role for water dissociation in the slow binding of phosphorus-containing transition-state-analogue inhibitors of thermolysin

4

1 reference

10.1021/BI00116A008

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11 November 2022

The stereoselective enzymatic synthesis of 9-beta-D-2'-deoxyribofuranosyl 1-deazapurine.

6

1 reference

10.1021/BI00116A008

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11 November 2022

The protonated form of 1-N6-etheno-[erythro-9-(2-hydroxy-3-nonyl)] adenine is identified at the active site of adenosine deaminase

7

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

Use of isotope effects to elucidate enzyme mechanisms

8

1 reference

10.1021/BI00116A008

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11 November 2022

Improved synthesis and antitumor activity of 1-deazaadenosine

10

1 reference

10.1021/BI00116A008

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11 November 2022

Catalysis of the covalent hydration of pteridine by adenosine aminohydrolase

12

1 reference

10.1021/BI00116A008

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11 November 2022

Adenosine deaminase and adenylate deaminase: comparative kinetic studies with transition state and ground state analogue inhibitors

15

1 reference

10.1021/BI00116A008

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11 November 2022

Transition-state stabilization by adenosine deaminase: 1,6-addition of water to purine ribonucleoside, the enzyme's affinity for 6-hydroxy-1,6-dihydropurine ribonucleoside, and the effective concentration of substrate water at the active site

19

1 reference

10.1021/BI00116A008

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11 November 2022

Major enhancement of the affinity of an enzyme for a transition-state analog by a single hydroxyl group

21

1 reference

10.1021/BI00116A008

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11 November 2022

Adenosine deaminase: solvent isotope and pH effects on the binding of transition-state and ground-state analogue inhibitors

23

1 reference

10.1021/BI00116A008

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11 November 2022

Adenosine deaminase converts purine riboside into an analogue of a reactive intermediate: a 13C NMR and kinetic study

24

1 reference

10.1021/BI00116A008

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11 November 2022

Protein structural changes accompanying formation of enzymatic transition states: tryptophan environment in ground-state and transition-state analogue complexes of adenosine deaminase.

25

1 reference

10.1021/BI00116A008

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11 November 2022

Adenosine deaminase: viscosity studies and the mechanism of binding of substrate and of ground- and transition-state analogue inhibitors.

26

1 reference

10.1021/BI00116A008

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11 November 2022

Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA.

27

1 reference

10.1021/BI00116A008

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11 November 2022

A quantum chemical study of the enzymatic deamination of benzoadenine derivatives. A theoretical model of the interactions occurring between nucleosides and the active site of adenosine deaminase.

28

1 reference

10.1021/BI00116A008

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11 November 2022

Calibration of stopped-flow spectrophotometers using a two-step disulfide exchange reaction.

29

1 reference

10.1021/BI00116A008

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11 November 2022

Immunoaffinity purification and fluorescence studies of human adenosine deaminase.

30

1 reference

10.1021/BI00116A008

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11 November 2022

Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase.

37

1 reference

10.1021/BI00116A008

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11 November 2022

Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations

38

1 reference

10.1021/BI00116A008

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11 November 2022

Analysis of progress curves by simulations generated by numerical integration

41

1 reference

10.1021/BI00116A008

https://api.crossref.org/works/10.1021/BI00116A008

11 November 2022

Identifiers

10.1021/BI00116A008

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/1731884

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