(Q51171104)

31 March 2018

title

Enhancement of carboplatin- and quercetin-induced cell death by roscovitine is Akt dependent and p53 independent in hepatoma cells. (English)

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31 March 2018

main subject

hepatocellular carcinoma

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Aanchal Sharma

1

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31 March 2018

Manoj Kumar Bhat

series ordinal

2

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31 March 2018

publication date

11 October 2011

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31 March 2018

Integrative Cancer Therapies

published in

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31 March 2018

volume

10

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31 March 2018

issue

4

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31 March 2018

page(s)

NP4-14

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31 March 2018

5-Fluorouracil: mechanisms of action and clinical strategies

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1 reference

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Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells

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You never know: Cdk inhibitors as anti-cancer drugs

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

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Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells.

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21 January 2018

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Synergistic down-regulation of signal transduction and cytotoxicity by tiazofurin and quercetin in human ovarian carcinoma cells.

21 January 2018

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Inhibition of Hsp27 and Hsp40 potentiates 5-fluorouracil and carboplatin mediated cell killing in hepatoma cells

21 January 2018

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Roscovitine synergizes with conventional chemo-therapeutic drugs to induce efficient apoptosis of human colorectal cancer cells

21 January 2018

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Cyclin-dependent kinase inhibitors sensitize tumor cells to nutlin-induced apoptosis: a potent drug combination.

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Roscovitine differentially affects asynchronously growing and synchronized human MCF-7 breast cancer cells

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Cell cycle regulatory protein 5 (Cdk5) is a novel downstream target of ERK in carboplatin induced death of breast cancer cells

21 January 2018

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p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.

21 January 2018

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Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells

21 January 2018

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Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion

21 January 2018

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Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival.

21 January 2018

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Hyperthermia-associated carboplatin resistance: differential role of p53, HSF1 and Hsp70 in hepatoma cells.

21 January 2018

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Recent progress in the discovery and development of cyclin-dependent kinase inhibitors

21 January 2018

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Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials

21 January 2018

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The effects of the CDK inhibitor seliciclib alone or in combination with cisplatin in human uterine sarcoma cell lines.

21 January 2018

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Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.

21 January 2018

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Roscovitine up-regulates p53 protein and induces apoptosis in human HeLaS(3) cervix carcinoma cells

21 January 2018

1 reference

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AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1534735411423922

1 reference

31 March 2018

1 reference

31 March 2018