(Q51194324)

1 April 2018

title

Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells. (English)

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1 April 2018

author name string

Chad N Brocker

1

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1 April 2018

Jiang Yue

2

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1 April 2018

Donghwan Kim

3

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1 April 2018

Aijuan Qu

4

1 reference

1 April 2018

Jessica A Bonzo

5

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1 April 2018

Frank J Gonzalez

6

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1 April 2018

publication date

12 January 2017

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1 April 2018

American Journal of Physiology - Gastrointestinal and Liver Physiology

published in

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1 April 2018

volume

312

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1 April 2018

issue

3

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1 April 2018

page(s)

G283-G299

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1 April 2018

Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies

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Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury

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Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.

22 May 2018

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Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice

22 May 2018

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22 May 2018

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Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress

22 May 2018

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PPARα-Dependent Activation of Cell Cycle Control and DNA Repair Genes in Hepatic Nonparenchymal Cells

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

22 May 2018

1 reference

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Hepatocyte-restricted constitutive activation of PPAR alpha induces hepatoproliferation but not hepatocarcinogenesis

22 May 2018

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Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

22 May 2018

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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

22 May 2018

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Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression

22 May 2018

1 reference

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CD36-dependent fatty acid uptake regulates expression of peroxisome proliferator activated receptors

22 May 2018

1 reference

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22 May 2018

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A new mathematical model for relative quantification in real-time RT-PCR

22 May 2018

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Role of hepatic non-parenchymal cells in the response of rat hepatocytes to the peroxisome proliferator nafenopin in vitro

22 May 2018

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Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Peroxisome proliferator-activated receptors: nuclear control of metabolism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Cytokines in non-genotoxic hepatocarcinogenesis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Normal growth and development in the absence of hepatic insulin-like growth factor I

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Role of kupffer cells in peroxisome proliferator-induced hepatocyte proliferation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

[Anti-fibrosis effects of fenofibrate in mice with hepatic fibrosis].

22 May 2018

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An efficient method to isolate and culture mouse Kupffer cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Isolation of nuclei for use in genome-wide DNase hypersensitivity assays to probe chromatin structure

14 August 2018

1 reference

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Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Mouse hepatocyte response to peroxisome proliferators: dependency on hepatic nonparenchymal cells and peroxisome proliferator activated receptor alpha (PPARalpha).

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5401987

14 August 2018

Identifiers

DOI

10.1152/AJPGI.00205.2016

1 reference

1 April 2018

PMC publication ID

5401987

1 reference

1 April 2018

PubMed publication ID

28082284

1 reference

1 April 2018