(Q51357843)

English

Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells.

scientific article published on 12 April 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

author name string

N Grankvist

1

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

L Amable

2

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

R E Honkanen

3

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

A Sjöholm

4

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

H Ortsäter

5

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

publication date

12 April 2012

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

55

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

7

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

2005-2015

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

https://scigraph.springernature.com/pub.10.1007/s00125-012-2541-1

0 references

Quantitative study of insulin secretion and clearance in normal and obese subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Diabetes mellitus and impaired pancreatic beta-cell proliferation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Mitochondrial functional state in clonal pancreatic beta-cells exposed to free fatty acids

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

The roles of ASK family proteins in stress responses and diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Protein phosphatase 5 in signal transduction.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Regulation of apoptosis signal-regulating kinase 1 (ASK1) by polyamine levels via protein phosphatase 5.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ).

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Prooxidative effects of green tea polyphenol (-)-epigallocatechin-3-gallate on the HIT-T15 pancreatic beta cell line

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Glucocorticoid receptor phosphorylation differentially affects target gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Protein phosphatase 5 protects neurons against amyloid-beta toxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2541-1

21 January 2018

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the metabolic effects of mixed meal and standard oral glucose tolerance test on glucose, insulin and C-peptide response in healthy, impaired glucose tolerance, mild and severe non-insulin-dependent diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A busy cell--endoplasmic reticulum stress in the pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Islet Volume but Unchanged Islet Number in ob/ob Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22526606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-012-2541-1

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22526606

ResearchGate publication ID

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