(Q51379331)

4 April 2018

title

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation. (English)

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4 April 2018

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2

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Dolors Serra Cucurull

10

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4 April 2018

Maria Ida Malandrino

3

Maria Ida Malandrino

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4 April 2018

Guillermina Asins

7

Guillermina Asins

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4 April 2018

Maria Sol Rodríguez-Peña

5

Maria Sol Rodríguez-Peña

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4 April 2018

Harald Petry

6

Harald Petry

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4 April 2018

Josep M Orellana-Gavaldà

1

Josep M Orellana-Gavaldà

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4 April 2018

author name string

Astrid Pañeda

4

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4 April 2018

Sander Van Deventer

8

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Fausto G Hegardt

9

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4 April 2018

language of work or name

English

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publication date

11 February 2011

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4 April 2018

published in

Hepatology

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volume

53

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issue

3

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4 April 2018

page(s)

821-832

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4 April 2018

Disordered lipid metabolism and the pathogenesis of insulin resistance

cites work

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7 January 2021

Obesity, Inflammation, and Insulin Resistance

1 reference

7 January 2021

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

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7 January 2021

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

1 reference

7 January 2021

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

1 reference

7 January 2021

Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition

1 reference

7 January 2021

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

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7 January 2021

CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance

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7 January 2021

Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids

1 reference

7 January 2021

Increased oxidative stress in obesity and its impact on metabolic syndrome

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7 January 2021

Superoxide activates mitochondrial uncoupling proteins

1 reference

7 January 2021

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

7 January 2021

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

1 reference

7 January 2021

T-ing up inflammation in fat

1 reference

7 January 2021

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

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7 January 2021

Adipocyte death, adipose tissue remodeling, and obesity complications

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7 January 2021

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

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7 January 2021

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes

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7 January 2021

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

1 reference

7 January 2021

Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1 alpha: implications for metabolic disease

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7 January 2021

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

1 reference

7 January 2021

The cryptic life style of adeno-associated virus

1 reference

7 January 2021

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

1 reference

7 January 2021

Mitochondrial injury in steatohepatitis.

1 reference

7 January 2021

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species

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7 January 2021

Inflammation and insulin resistance

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7 January 2021

Ceramides in insulin resistance and lipotoxicity

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7 January 2021

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

1 reference

7 January 2021

Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over beta-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states

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7 January 2021

In vitro and in vivo comparative study of chimeric liver-specific promoters

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7 January 2021

Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element.

1 reference

7 January 2021

Insect cells as a factory to produce adeno-associated virus type 2 vectors

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7 January 2021

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

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7 January 2021

14CO2 production is no adequate measure of [14C]fatty acid oxidation.

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7 January 2021

Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion

1 reference

7 January 2021

Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver

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7 January 2021

Identifiers

DOI

10.1002/HEP.24140

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4 April 2018

release_sooynmzqovhf5gkwakthtyk3ve

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sooynmzqovhf5gkwakthtyk3ve

24 November 2022

mapped directly with Wikidata item

PubMed ID

21319201

1 reference

4 April 2018