(Q51389950)

4 April 2018

title

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in alpha-tropomyosin. (English)

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3

Michael J Ackerman

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4 April 2018

author name string

Audrey N Chang

series ordinal

1

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4 April 2018

Keita Harada

series ordinal

2

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4 April 2018

James D Potter

series ordinal

4

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4 April 2018

language of work or name

English

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publication date

25 July 2005

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4 April 2018

Journal of Biological Chemistry

published in

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volume

280

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page(s)

34343-34349

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issue

40

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4 April 2018

Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Prevalence and severity of "benign" mutations in the beta-myosin heavy chain, cardiac troponin T, and alpha-tropomyosin genes in hypertrophic cardiomyopathy

21 January 2018

1 reference

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Variable clinical manifestation of a novel missense mutation in the alpha-tropomyosin (TPM1) gene in familial hypertrophic cardiomyopathy.

21 January 2018

1 reference

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Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

21 January 2018

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Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy

21 January 2018

1 reference

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Effects of side-chain characteristics on stability and oligomerization state of a de novo-designed model coiled-coil: 20 amino acid substitutions in position "d".

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

The influence of native tropomyosin on the ATP threshold for turbidity development of actomyosin and myofibril suspensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Extraction of proteins other than myosin from the isolated rabbit myofibril

21 January 2018

1 reference

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Natural tropomyosin and the factor sensitizing actomyosin adenosine triphosphatase to ethylenedioxybis(ethyleneamino)tetra-acetic acid

21 January 2018

1 reference

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The adeonosine-triphosphatase activity of desensitized actomyosin

21 January 2018

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Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Familial Hypertrophic Cardiomyopathy-linked Alterations in Ca2+ Binding of Human Cardiac Myosin Regulatory Light Chain Affect Cardiac Muscle Contraction

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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The inhibitory effects of monovalent ions on force development in detergent-skinned ventricular muscle from guinea-pig.

21 January 2018

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Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

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Functional analysis of a troponin I (R145G) mutation associated with familial hypertrophic cardiomyopathy

21 January 2018

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Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility.

21 January 2018

1 reference

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Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.

21 January 2018

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Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin

21 January 2018

1 reference

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Effect of Hypertrophic Cardiomyopathy Mutations in Human Cardiac Muscle α -tropomyosin (Asp175Asn and Glu180Gly) on the Regulatory Properties of Human Cardiac Troponin Determined by in vitro Motility Assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by beta-blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505014200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505014200

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4 April 2018

PubMed ID

16043485

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4 April 2018