(Q51392738)

4 April 2018

title

TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction. (English)

1 reference

4 April 2018

Kedar Ghimire

4

0 references

Stephanie M Mutchler

object named as

Stephanie M Mutchler

6

0 references

Adam C Straub

22

object named as

Adam C Straub

1 reference

4 April 2018

21

Ana L Mora

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4 April 2018

author name string

Natasha M Rogers

1

1 reference

4 April 2018

Maryam Sharifi-Sanjani

2

1 reference

4 April 2018

Mingyi Yao

3

1 reference

4 April 2018

Raquel Bienes-Martinez

5

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4 April 2018

Heather E Knupp

7

1 reference

4 April 2018

Jeffrey Baust

8

1 reference

4 April 2018

Enrico M Novelli

9

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4 April 2018

Mark Ross

10

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4 April 2018

Claudette St Croix

11

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4 April 2018

Johannes C Kutten

12

1 reference

4 April 2018

Caitlin A Czajka

13

1 reference

4 April 2018

John C Sembrat

14

1 reference

4 April 2018

Mauricio Rojas

15

1 reference

4 April 2018

David Labrousse-Arias

16

1 reference

4 April 2018

Timothy N Bachman

17

1 reference

4 April 2018

Rebecca R Vanderpool

18

1 reference

4 April 2018

Brian S Zuckerbraun

19

1 reference

4 April 2018

Hunter C Champion

20

1 reference

4 April 2018

Richard A Bilonick

23

1 reference

4 April 2018

Maria J Calzada

24

1 reference

4 April 2018

Jeffrey S Isenberg

25

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4 April 2018

publication date

13 October 2016

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4 April 2018

published in

Cardiovascular Research

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4 April 2018

volume

113

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4 April 2018

issue

1

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4 April 2018

page(s)

15-29

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4 April 2018

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction

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Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury

22 May 2018

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Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

22 May 2018

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The role of collagen synthesis in ventricular and vascular adaptation to hypoxic pulmonary hypertension

22 May 2018

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Peroxisome proliferator-activated receptor gamma (PPARγ) regulates thrombospondin-1 and Nox4 expression in hypoxia-induced human pulmonary artery smooth muscle cell proliferation

22 May 2018

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Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.

22 May 2018

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Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates

22 May 2018

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The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.

22 May 2018

1 reference

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Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.

22 May 2018

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Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension

22 May 2018

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Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension

22 May 2018

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22 May 2018

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Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties

22 May 2018

1 reference

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Deciphering the intricate regulatory mechanisms for the cellular choice between cell repair, apoptosis or senescence in response to damaging signals

22 May 2018

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Mechanistic insights into reprogramming to induced pluripotency.

22 May 2018

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Characteristics of interstitial fibrosis and inflammatory cell infiltration in right ventricles of systemic sclerosis-associated pulmonary arterial hypertension

22 May 2018

1 reference

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Thrombospondin-1 inhibits VEGF receptor-2 signaling by disrupting its association with CD47.

22 May 2018

1 reference

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Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation

22 May 2018

1 reference

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Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension

22 May 2018

1 reference

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Thrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective.

22 May 2018

1 reference

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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

22 May 2018

1 reference

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Diagnosis and assessment of pulmonary arterial hypertension.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Molecular pathogenesis of pulmonary arterial hypertension

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

CD47: a new target in cardiovascular therapy.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Targeting of Miz-1 is essential for Myc-mediated apoptosis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Diagnosis and differential assessment of pulmonary arterial hypertension

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

The endothelin system in pulmonary arterial hypertension

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Thrombospondins 1 and 2 function as inhibitors of angiogenesis

22 May 2018

1 reference

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Haemodynamic evaluation of pulmonary hypertension.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Pathobiology of pulmonary hypertension. Extracellular matrix

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

The Myc/Max/Mad network and the transcriptional control of cell behavior

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Quantitation of platelet fibrinogen and thrombospondin in Glanzmann's thrombasthenia by electroimmunoassay

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Localization of immunoreactive endothelin and proendothelin in the human lung

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

CD47 regulates renal tubular epithelial cell self-renewal and proliferation following renal ischemia reperfusion.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

A novel murine model of severe pulmonary arterial hypertension

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Global deletion of thrombospondin-1 increases cardiac and skeletal muscle capillarity and exercise capacity in mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

A solution to the problem of separation in logistic regression.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Discrepant distribution of big endothelin (ET)-1 and ET receptors in the pulmonary artery.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5220673

Increasing Survival of Ischemic Tissue by Targeting CD47

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVW218

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVW218

21 January 2018

12 December 2020

[The expression of thrombospondin-1 in serum and pulmonary arterioles of hypoxic pulmonary hypertension rats]

1 reference

12 December 2020

Circulating platelet aggregates indicative of in vivo platelet activation in pulmonary hypertension

1 reference

12 December 2020

Alpha4beta1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo

1 reference

12 December 2020

Interferon-{beta} inhibits bleomycin-induced lung fibrosis by decreasing transforming growth factor-{beta} and thrombospondin

1 reference

12 December 2020

Isolation of endothelial cells from murine tissue

1 reference

12 December 2020

Platelet activation and fibrinopeptide formation in pulmonary hypertension

1 reference

12 December 2020

Improved right ventricular-vascular coupling during active pulmonary hypertension

1 reference

12 December 2020

Formation of plexiform lesions in experimental severe pulmonary arterial hypertension

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVW218

1 reference

4 April 2018

PMC publication ID

5220673

1 reference

4 April 2018

PubMed publication ID

27742621

1 reference

4 April 2018