(Q51429610)

5 April 2018

title

Vinpocetine selectively inhibits neurotransmitter release triggered by sodium channel activation. (English)

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5 April 2018

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M Sitges

1

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5 April 2018

V Nekrassov

series ordinal

2

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5 April 2018

publication date

1 December 1999

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5 April 2018

published in

Neurochemical Research

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5 April 2018

volume

24

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5 April 2018

issue

12

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5 April 2018

page(s)

1585-1591

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5 April 2018

https://scigraph.springernature.com/pub.10.1023/a:1021164418478

exact match

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Comparative neuroprotective effects of pentobarbital, vinpocetine, flunarizine and ifenprodil on ischemic neuronal damage in the gerbil hippocampus

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Hippocampal slices: glutamate overflow and cellular damage from ischemia are reduced by sodium-channel blockade.

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Depolarization of rat brain synaptosomes increases phosphorylation of voltage-sensitive sodium channels.

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Vincamine and vincanol are potent blockers of voltage-gated Na+ channels.

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12 December 2020

omega-Aga IVA selectively inhibits the calcium-dependent fraction of the evoked release of [3H]GABA from synaptosomes

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12 December 2020

Vinpocetine prevents ischemic cell damage in rat hippocampus.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Vinpocetine is a highly potent neuroprotectant against veratridine-induced cell death in primary cultures of rat cerebral cortex

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12 December 2020

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12 December 2020

Characterization of the type of calcium channel primarily regulating GABA exocytosis from brain nerve endings

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12 December 2020

Effects of external pH variations on brain presynaptic sodium and calcium channels; repercussion on the evoked release of amino acid neurotransmitters.

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The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum

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Excitotoxic cell death

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12 December 2020

Nootropic agent vinpocetine blocks delayed rectified potassium currents more strongly than high-threshold calcium currents

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The neuroprotective drug vinpocetine prevents veratridine-induced [Na+]i and [Ca2+]i rise in synaptosomes

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12 December 2020

Protective effects of vinpocetine and structurally related drugs on the lethal consequences of hypoxia in mice

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12 December 2020

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12 December 2020

Pharmacological modulation of voltage-gated Na+ channels: a rational and effective strategy against ischemic brain damage.

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12 December 2020

Vinpocetine is as potent as phenytoin to block voltage-gated Na+ channels in rat cortical neurons.

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12 December 2020

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

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12 December 2020

Na+ channels as targets for neuroprotective drugs

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1023/A:1021164418478

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5 April 2018

Dimensions Publication ID

1051842587

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5 April 2018