(Q51496187)

5 April 2018

title

Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys. (English)

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5 April 2018

author name string

C Jerome

series ordinal

1

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5 April 2018

M Missbach

series ordinal

2

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5 April 2018

R Gamse

series ordinal

3

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5 April 2018

language of work or name

English

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publication date

5 March 2011

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5 April 2018

Osteoporosis International

published in

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5 April 2018

volume

23

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5 April 2018

issue

1

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5 April 2018

page(s)

339-349

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5 April 2018

https://scigraph.springernature.com/pub.10.1007/s00198-011-1593-2

exact match

0 references

cites work

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The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics

21 January 2018

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Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

21 January 2018

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Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

21 January 2018

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Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate

21 January 2018

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A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys.

21 January 2018

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Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys

21 January 2018

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

21 January 2018

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The androgenic anabolic steroid nandrolone decanoate prevents osteopenia and inhibits bone turnover in ovariectomized cynomolgus monkeys

21 January 2018

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Changes in micro-CT 3D bone parameters reflect effects of a potent cathepsin K inhibitor (SB-553484) on bone resorption and cortical bone formation in ovariectomized mice.

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Effects of raloxifene on bone density, biomarkers, and histomorphometric and biomechanical measures in ovariectomized cynomolgus monkeys

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Bisphosphonates do not inhibit periosteal bone formation in estrogen deficient animals and allow enhanced bone modeling in response to mechanical loading

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Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib.

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Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts

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Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

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Treatment with human parathyroid hormone (1-34) for 18 months increases cancellous bone volume and improves trabecular architecture in ovariectomized cynomolgus monkeys (Macaca fascicularis)

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Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo

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10.1007/S00198-011-1593-2

Identifiers

DOI

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5 April 2018

1 reference

5 April 2018