(Q36532578)

14 August 2017

1 reference

title

Future anti-catabolic therapeutic targets in bone disease (English)

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14 August 2017

Brendan F Boyce

1

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14 August 2017

Lianping Xing

2

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14 August 2017

Zhenqiang Yao

3

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14 August 2017

William C Shakespeare

4

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14 August 2017

Yihan Wang

5

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14 August 2017

Chester A Metcalf

6

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14 August 2017

Raji Sundaramoorthi

7

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14 August 2017

David C Dalgarno

8

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14 August 2017

John D Iuliucci

9

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14 August 2017

Tomi K Sawyer

10

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14 August 2017

language of work or name

English

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publication date

1 April 2006

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Annals of the New York Academy of Sciences

14 August 2017

published in

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14 August 2017

volume

1068

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14 August 2017

page(s)

447-457

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

RANK is essential for osteoclast and lymph node development

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Osteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Osteoclast differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Antiosteoporotic activity of the water extract of Dioscorea spongiosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Determination of bone markers in pycnodysostosis: effects of cathepsin K deficiency on bone matrix degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

An azepanone-based inhibitor of human cathepsin K with improved oral bioavailability in the rat and the monkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

A novel inhibitor of vacuolar ATPase, FR167356, which can discriminate between osteoclast vacuolar ATPase and lysosomal vacuolar ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

PI3-kinase and TOR: PIKTORing cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Sirolimus: its discovery, biological properties, and mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Targeting simian virus 40 T antigen to the osteoclast in transgenic mice causes osteoclast tumors and transformation and apoptosis of osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Src kinase activity is essential for osteoclast function

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

4-anilino-3-quinolinecarbonitriles: an emerging class of kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Bone-targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.042

21 January 2018

Identifiers

DOI

10.1196/ANNALS.1346.042

1 reference

14 August 2017

1 reference