(Q51521807)

6 April 2018

title

Continuous flow micro-bioreactors for the production of biopharmaceuticals: the effect of geometry, surface texture, and flow rate. (English)

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6 April 2018

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Erika García-López

2

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Sergio Camacho-León

object named as

Sergio Camacho-León

3

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Mario Moisés Alvarez

object named as

Mario Moisés Alvarez

Maria Del Refugio Rocha-Pizaña

11

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object named as

María Del Refugio Rocha-Pizaña

4

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author name string

Lucía D Garza-García

1

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6 April 2018

Felipe López-Pacheco

5

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6 April 2018

Julián López-Meza

6

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6 April 2018

Diana Araiz-Hernández

7

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6 April 2018

Eduardo J Tapia-Mejía

8

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6 April 2018

Grissel Trujillo-de Santiago

9

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6 April 2018

Ciro A Rodríguez-González

10

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6 April 2018

publication date

1 April 2014

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6 April 2018

published in

Lab on a Chip

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6 April 2018

volume

14

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6 April 2018

issue

7

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6 April 2018

page(s)

1320-1329

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6 April 2018

State-of-the-art in downstream processing of monoclonal antibodies: process trends in design and validation

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

21 January 2018

Therapeutic proteins.

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Marketed therapeutic antibodies compendium

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Investigation of metabolic variability observed in extended fed batch cell culture

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CHO cells in biotechnology for production of recombinant proteins: current state and further potential

21 January 2018

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Integrated continuous production of recombinant therapeutic proteins.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3LC51301G

Defining process design space for monoclonal antibody cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Fundamentals of microfluidic cell culture in controlled microenvironments

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3LC51301G

Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice.

21 January 2018

1 reference

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Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

21 January 2018

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Organs-on-a-chip for drug discovery

21 January 2018

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Enhancement of static incubation time in microfluidic cell culture platforms exploiting extended air-liquid interface

21 January 2018

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A novel microfluidic co-culture system for investigation of bacterial cancer targeting

21 January 2018

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Reconstituting organ-level lung functions on a chip

21 January 2018

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A continuous perfusion microplate for cell culture.

21 January 2018

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A standalone perfusion platform for drug testing and target validation in micro-vessel networks

21 January 2018

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Integrated microdevice for long-term automated perfusion culture without shear stress and real-time electrochemical monitoring of cells

21 January 2018

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Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3LC51301G

Systematic single-cell analysis of Pichia pastoris reveals secretory capacity limits productivity

21 January 2018

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A practical guide to microfluidic perfusion culture of adherent mammalian cells.

21 January 2018

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A biopharmaceutical plant on a chip: continuous micro-devices for the production of monoclonal antibodies.

21 January 2018

1 reference

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Engineers are from PDMS-land, Biologists are from Polystyrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Study of long-term viability of endothelial cells for lab-on-a-chip devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Effect of channel geometry on cell adhesion in microfluidic devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

21 January 2018

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https://api.crossref.org/works/10.1039%2FC3LC51301G

Critical stresses for cancer cell detachment in microchannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

A multi-shear perfusion bioreactor for investigating shear stress effects in endothelial cell constructs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

Wettability versus roughness of engineering surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3LC51301G

21 January 2018

Identifiers

DOI

10.1039/C3LC51301G

1 reference

6 April 2018

1 reference

6 April 2018