(Q51598582)

English

Kinetic interaction analysis of human interleukin 5 receptor alpha mutants reveals a unique binding topology and charge distribution for cytokine recognition.

scientific article published on 7 December 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Kinetic interaction analysis of human interleukin 5 receptor alpha mutants reveals a unique binding topology and charge distribution for cytokine recognition. (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Gianfranco Pasut

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Gianfranco Pasut

2

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author name string

Tetsuya Ishino

1

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Jeffery Scibek

3

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Irwin Chaiken

4

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

language of work or name

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publication date

7 December 2003

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

279

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

10

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

9547-9556

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

Biological and molecular characteristics of interleukin-5 and its receptor.

1 reference

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A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

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A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands

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Molecular cloning and expression of the human interleukin 5 receptor

1 reference

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21 January 2018

Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit

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21 January 2018

Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.

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A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5

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Mutagenesis in the C-terminal region of human interleukin 5 reveals a central patch for receptor alpha chain recognition

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21 January 2018

Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist

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Randomization of the receptor alpha chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop

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Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site

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Comparative protein modelling by satisfaction of spatial restraints

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Covalent modification of the interleukin-5 receptor by isothiazolones leads to inhibition of the binding of interleukin-5.

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21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

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21 January 2018

Recognition of errors in three-dimensional structures of proteins

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21 January 2018

Assessment of protein models with three-dimensional profiles

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21 January 2018

Multisite mutagenesis of interleukin 5 differentiates sites for receptor recognition and receptor activation

1 reference

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21 January 2018

Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites

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21 January 2018

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21 January 2018

Identification of regions within the third FnIII-like domain of the IL-5Ralpha involved in IL-5 interaction

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21 January 2018

Crucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognition

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21 January 2018

Kinetics of protein-protein association explained by Brownian dynamics computer simulation

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21 January 2018

The propagation of binding interactions to remote sites in proteins: analysis of the binding of the monoclonal antibody D1.3 to lysozyme

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21 January 2018

MOLMOL: a program for display and analysis of macromolecular structures

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Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes

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21 January 2018

Structural design and molecular evolution of a cytokine receptor superfamily

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Structural and physicochemical analysis of the reaction between the anti-lysozyme antibody D1.3 and the anti-idiotopic antibodies E225 and E5.2

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Identifiers

10.1074/JBC.M309327200

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/14662768

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